Predittori di mortalità a breve termine in soggetti anziani con ictus ischemico

Translated title of the contribution: Predictors of short-term mortality in elderly people with ischemic stroke

G. Guera, M. Ranzini, A. R. Atti, C. Benedeti, A. Cherubini, R. Felin, Giovanni Zuliani

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction. Stroke is the third cause of death in elderly people living in Western Countries. The identification of prognostic factors after ischemic injury is important in order to carry out therapeutic and preventive strategies. Aim of the study. To estimate the association between clinical and laboratory parameters and 30-day mortality in a sample of elderly people with stroke. Methods. Four hundred sixty nine elderly subjects (middle age: 80.0 years) admitted for ischemic stroke were enrolled. Our data included: 1) clinical features; 2) laboratory tests; 3) clinical history. All patients undergone brain CT scan. Stroke type was classified according to Oxfordshire Community Stroke Project (OCSP) System. Results. 130 subjects died within 30 days from admission, with a total mortality of 27.7%. At multivariate logistic regression analysis the presence of altered state of consciousness (OR: 11.80; C.I. 95%: 5.50-24.00), heart failure (OR: 3.06; C.I. 95%: 1.04-8.80) and age (OR: 1.04; C.I. 95%: 1.002-1.09) was independently associated with short-time mortality. In patients with altered state of consciousness (mortality: 63.6%) only hyperglycemia (III vs I tertile, OR: 9.60; C.I. 95%: 1.65-52.50) was associated to mortality at multivariate analysis. Conclusions. Our study shows the significance of altered state of consciousness and heart failure in short-term prognostic stratification of elderly people with ischemic stroke. Our results confirm the role of post-stroke hyperglycemia as a marker of short-time mortality, in particular when associated to altered state of consciousness.

Translated title of the contributionPredictors of short-term mortality in elderly people with ischemic stroke
Original languageItalian
Pages (from-to)16-22
Number of pages7
JournalGiornale di Gerontologia
Volume57
Issue number1
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Ageing
  • Geriatrics and Gerontology

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