Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy

Antonella Antenora, Dario Bruzzese, Maria Lieto, Alessandro Roca, Maria Teresa Florio, Silvio Peluso, Francesco Saccà, Giuseppe De Michele, Filippo Maria Santorelli, Alessandro Filla

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

One hundred-eighteen spinocerebellar ataxia type 2 patients from 35 distinct families personally observed between 1973 and 2016 were retrospectively reviewed. The time point of data collection was 1 January 2017. Thirty-one patients were confined to wheelchair. The median time to wheelchair was 21 years (95% CI, 17.5–24.6). Thirty-seven patients were deceased. The median time to death was 25 years (95% CI, 22.9–27.1). CAG repeat number and ataxia score at first visit influenced the time to wheelchair and death.

Original languageEnglish
JournalNeurological Sciences
DOIs
Publication statusAccepted/In press - Jan 1 2018

Fingerprint

Spinocerebellar Ataxias
Italy
Wheelchairs
Survival
Population
Ataxia

Keywords

  • Ataxia scale
  • CAG repeats
  • SCA2
  • Survival

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Antenora, A., Bruzzese, D., Lieto, M., Roca, A., Florio, M. T., Peluso, S., ... Filla, A. (Accepted/In press). Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy. Neurological Sciences. https://doi.org/10.1007/s10072-018-3504-1

Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy. / Antenora, Antonella; Bruzzese, Dario; Lieto, Maria; Roca, Alessandro; Florio, Maria Teresa; Peluso, Silvio; Saccà, Francesco; De Michele, Giuseppe; Santorelli, Filippo Maria; Filla, Alessandro.

In: Neurological Sciences, 01.01.2018.

Research output: Contribution to journalArticle

Antenora, A, Bruzzese, D, Lieto, M, Roca, A, Florio, MT, Peluso, S, Saccà, F, De Michele, G, Santorelli, FM & Filla, A 2018, 'Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy', Neurological Sciences. https://doi.org/10.1007/s10072-018-3504-1
Antenora, Antonella ; Bruzzese, Dario ; Lieto, Maria ; Roca, Alessandro ; Florio, Maria Teresa ; Peluso, Silvio ; Saccà, Francesco ; De Michele, Giuseppe ; Santorelli, Filippo Maria ; Filla, Alessandro. / Predictors of survival in spinocerebellar ataxia type 2 population from Southern Italy. In: Neurological Sciences. 2018.
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