Predictors of unfavourable repeat biopsy results in men participating in a prospective active surveillance program

Meelan Bul, Roderick C N Van Den Bergh, Antti Rannikko, Riccardo Valdagni, Tom Pickles, Chris H. Bangma, Monique J. Roobol

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Active surveillance (AS) protocols for low-risk prostate cancer (PCa) generally include repeat prostate biopsies at predefined follow-up intervals. Objective: To study the outcome of routinely obtained 1-yr repeat biopsies and factors predicting reclassification to higher risk, to contribute to risk stratification for men on AS. Design, setting, and participants: We analysed men with low-risk PCa (clinical stage ≤T2, prostate-specific antigen (PSA) ≤10 ng/ml, PSA density

Original languageEnglish
Pages (from-to)370-377
Number of pages8
JournalEuropean Urology
Volume61
Issue number2
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Active surveillance
  • Biopsy
  • Disease progression
  • Prostate-specific antigen
  • Prostatic neoplasms
  • Reclassification
  • Risk

ASJC Scopus subject areas

  • Urology

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