Predictors of unfavourable repeat biopsy results in men participating in a prospective active surveillance program

Meelan Bul; Roderick C N Van Den Bergh; Antti Rannikko; Riccardo Valdagni; Tom Pickles; Chris H. Bangma; Monique J. Roobol

doi:10.1016/j.eururo.2011.06.027

Predictors of unfavourable repeat biopsy results in men participating in a prospective active surveillance program

Meelan Bul, Roderick C N Van Den Bergh, Antti Rannikko, Riccardo Valdagni, Tom Pickles, Chris H. Bangma, Monique J. Roobol

Fondazione IRCCS Istituto Nazionale dei Tumori

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Active surveillance (AS) protocols for low-risk prostate cancer (PCa) generally include repeat prostate biopsies at predefined follow-up intervals. Objective: To study the outcome of routinely obtained 1-yr repeat biopsies and factors predicting reclassification to higher risk, to contribute to risk stratification for men on AS. Design, setting, and participants: We analysed men with low-risk PCa (clinical stage ≤T2, prostate-specific antigen (PSA) ≤10 ng/ml, PSA density

Original language	English
Pages (from-to)	370-377
Number of pages	8
Journal	European Urology
Volume	61
Issue number	2
DOIs	https://doi.org/10.1016/j.eururo.2011.06.027
Publication status	Published - Feb 2012

Keywords

Active surveillance
Biopsy
Disease progression
Prostate-specific antigen
Prostatic neoplasms
Reclassification
Risk

ASJC Scopus subject areas

Urology

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Predictors of unfavourable repeat biopsy results in men participating in a prospective active surveillance program. / Bul, Meelan; Van Den Bergh, Roderick C N; Rannikko, Antti; Valdagni, Riccardo; Pickles, Tom; Bangma, Chris H.; Roobol, Monique J.

In: European Urology, Vol. 61, No. 2, 02.2012, p. 370-377.

Research output: Contribution to journal › Article › peer-review

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abstract = "Background: Active surveillance (AS) protocols for low-risk prostate cancer (PCa) generally include repeat prostate biopsies at predefined follow-up intervals. Objective: To study the outcome of routinely obtained 1-yr repeat biopsies and factors predicting reclassification to higher risk, to contribute to risk stratification for men on AS. Design, setting, and participants: We analysed men with low-risk PCa (clinical stage ≤T2, prostate-specific antigen (PSA) ≤10 ng/ml, PSA density ",

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AU - Pickles, Tom

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KW - Prostatic neoplasms

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