Predominant expression of σ and ε globin genes in human leukemia K-562(S6) variant cell line

R. Gambari; G. Raschellà; R. Biagini; M. Tripodi; M. G. Farace; A. Romeo; A. Fantoni

doi:10.1007/BF01963156

Predominant expression of σ and ε globin genes in human leukemia K-562(S6) variant cell line

R. Gambari, G. Raschellà, R. Biagini, M. Tripodi, M. G. Farace, A. Romeo, A. Fantoni

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article

Abstract

In the human leukemia K-562(S6) cell line (a) the accumulation of a-globin chains is low or absent, (b) ζ-globin gene expression is correlated with expression of ε-chains and (c) the genes responsible for the terminal cell division are not operated within 8-12 cell cycles, while K-562 (S6) cells are fully induced to erythroid differentiation.

Original language	English
Pages (from-to)	415-416
Number of pages	2
Journal	Experientia
Volume	39
Issue number	4
DOIs	https://doi.org/10.1007/BF01963156
Publication status	Published - 1983

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ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

Gambari, R., Raschellà, G., Biagini, R., Tripodi, M., Farace, M. G., Romeo, A., & Fantoni, A. (1983). Predominant expression of σ and ε globin genes in human leukemia K-562(S6) variant cell line. Experientia, 39(4), 415-416. https://doi.org/10.1007/BF01963156

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10.1007/BF01963156