Predominant expression of σ and ε globin genes in human leukemia K-562(S6) variant cell line

R. Gambari, G. Raschellà, R. Biagini, M. Tripodi, M. G. Farace, A. Romeo, A. Fantoni

Research output: Contribution to journalArticlepeer-review

Abstract

In the human leukemia K-562(S6) cell line (a) the accumulation of a-globin chains is low or absent, (b) ζ-globin gene expression is correlated with expression of ε-chains and (c) the genes responsible for the terminal cell division are not operated within 8-12 cell cycles, while K-562 (S6) cells are fully induced to erythroid differentiation.

Original languageEnglish
Pages (from-to)415-416
Number of pages2
JournalExperientia
Volume39
Issue number4
DOIs
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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