Preexistent anti-HLA-DR antibodies and kidney graft survival

G. Sirchia, F. Mercuriali, M. Scalamogna, V. Rosso di San Secondo, C. Pizzi, F. Poli, C. Fortis, N. Greppi

Research output: Contribution to journalArticlepeer-review

Abstract

The influence of preexistent anti-HLA-DR antibodies on the outcome of the graft has been retrospectively evaluated in 165 cadaver-kidney first transplants. All the patients considered had been transfused and homogeneously shared about two HLA-A, -B identities with their kidney donors. The outcomes of the grafts in the long run were significantly worse in patients with preexistent anti-HLA-DR lymphocytotoxic antibodies, either associated with anti-HLA-A, -B, -C or alone.

Original languageEnglish
Pages (from-to)950-953
Number of pages4
JournalTransplantation Proceedings
Volume11
Issue number1
Publication statusPublished - 1979

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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