Prefontal cortex in long-term memory: An "interference" approach using magnetic stimulation

Simone Rossi, Stefano F. Cappa, Claudio Babiloni, Patrizio Pasqualetti, Carlo Miniussi, Filippo Carducci, Fabio Babiloni, Paolo M. Rossini

Research output: Contribution to journalArticle

191 Citations (Scopus)

Abstract

Neuroimaging has consistently shown engagement of the prefrontal cortex during episodic memory tasks, but the functional relevance of this metabolic/hemodynamic activation in memory processing is still to be determined. We used repetitive transcranial magnetic stimulation (rTMS) to transiently interfere with either left or right prefrontal brain activity during the encoding or retrieval of pictures showing complex scenes. We found that the right dorsolateral prefrontal cortex (DLPFC) was crucial for the retrieval of the encoded pictorial information, whereas the left DLPFC was involved in encoding operations. This 'interference' approach allowed us to establish whether a cortical area activated by a memory task actually contributes to behavioral performance.

Original languageEnglish
Pages (from-to)948-952
Number of pages5
JournalNature Neuroscience
Volume4
Issue number9
DOIs
Publication statusPublished - 2001

Fingerprint

Long-Term Memory
Prefrontal Cortex
Episodic Memory
Transcranial Magnetic Stimulation
Neuroimaging
Hemodynamics
Brain

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Rossi, S., Cappa, S. F., Babiloni, C., Pasqualetti, P., Miniussi, C., Carducci, F., ... Rossini, P. M. (2001). Prefontal cortex in long-term memory: An "interference" approach using magnetic stimulation. Nature Neuroscience, 4(9), 948-952. https://doi.org/10.1038/nn0901-948

Prefontal cortex in long-term memory : An "interference" approach using magnetic stimulation. / Rossi, Simone; Cappa, Stefano F.; Babiloni, Claudio; Pasqualetti, Patrizio; Miniussi, Carlo; Carducci, Filippo; Babiloni, Fabio; Rossini, Paolo M.

In: Nature Neuroscience, Vol. 4, No. 9, 2001, p. 948-952.

Research output: Contribution to journalArticle

Rossi, S, Cappa, SF, Babiloni, C, Pasqualetti, P, Miniussi, C, Carducci, F, Babiloni, F & Rossini, PM 2001, 'Prefontal cortex in long-term memory: An "interference" approach using magnetic stimulation', Nature Neuroscience, vol. 4, no. 9, pp. 948-952. https://doi.org/10.1038/nn0901-948
Rossi S, Cappa SF, Babiloni C, Pasqualetti P, Miniussi C, Carducci F et al. Prefontal cortex in long-term memory: An "interference" approach using magnetic stimulation. Nature Neuroscience. 2001;4(9):948-952. https://doi.org/10.1038/nn0901-948
Rossi, Simone ; Cappa, Stefano F. ; Babiloni, Claudio ; Pasqualetti, Patrizio ; Miniussi, Carlo ; Carducci, Filippo ; Babiloni, Fabio ; Rossini, Paolo M. / Prefontal cortex in long-term memory : An "interference" approach using magnetic stimulation. In: Nature Neuroscience. 2001 ; Vol. 4, No. 9. pp. 948-952.
@article{d33c8927f9364c5f94d25a61d25d3dc1,
title = "Prefontal cortex in long-term memory: An {"}interference{"} approach using magnetic stimulation",
abstract = "Neuroimaging has consistently shown engagement of the prefrontal cortex during episodic memory tasks, but the functional relevance of this metabolic/hemodynamic activation in memory processing is still to be determined. We used repetitive transcranial magnetic stimulation (rTMS) to transiently interfere with either left or right prefrontal brain activity during the encoding or retrieval of pictures showing complex scenes. We found that the right dorsolateral prefrontal cortex (DLPFC) was crucial for the retrieval of the encoded pictorial information, whereas the left DLPFC was involved in encoding operations. This 'interference' approach allowed us to establish whether a cortical area activated by a memory task actually contributes to behavioral performance.",
author = "Simone Rossi and Cappa, {Stefano F.} and Claudio Babiloni and Patrizio Pasqualetti and Carlo Miniussi and Filippo Carducci and Fabio Babiloni and Rossini, {Paolo M.}",
year = "2001",
doi = "10.1038/nn0901-948",
language = "English",
volume = "4",
pages = "948--952",
journal = "Nature Neuroscience",
issn = "1097-6256",
publisher = "Nature Publishing Group",
number = "9",

}

TY - JOUR

T1 - Prefontal cortex in long-term memory

T2 - An "interference" approach using magnetic stimulation

AU - Rossi, Simone

AU - Cappa, Stefano F.

AU - Babiloni, Claudio

AU - Pasqualetti, Patrizio

AU - Miniussi, Carlo

AU - Carducci, Filippo

AU - Babiloni, Fabio

AU - Rossini, Paolo M.

PY - 2001

Y1 - 2001

N2 - Neuroimaging has consistently shown engagement of the prefrontal cortex during episodic memory tasks, but the functional relevance of this metabolic/hemodynamic activation in memory processing is still to be determined. We used repetitive transcranial magnetic stimulation (rTMS) to transiently interfere with either left or right prefrontal brain activity during the encoding or retrieval of pictures showing complex scenes. We found that the right dorsolateral prefrontal cortex (DLPFC) was crucial for the retrieval of the encoded pictorial information, whereas the left DLPFC was involved in encoding operations. This 'interference' approach allowed us to establish whether a cortical area activated by a memory task actually contributes to behavioral performance.

AB - Neuroimaging has consistently shown engagement of the prefrontal cortex during episodic memory tasks, but the functional relevance of this metabolic/hemodynamic activation in memory processing is still to be determined. We used repetitive transcranial magnetic stimulation (rTMS) to transiently interfere with either left or right prefrontal brain activity during the encoding or retrieval of pictures showing complex scenes. We found that the right dorsolateral prefrontal cortex (DLPFC) was crucial for the retrieval of the encoded pictorial information, whereas the left DLPFC was involved in encoding operations. This 'interference' approach allowed us to establish whether a cortical area activated by a memory task actually contributes to behavioral performance.

UR - http://www.scopus.com/inward/record.url?scp=0034863837&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034863837&partnerID=8YFLogxK

U2 - 10.1038/nn0901-948

DO - 10.1038/nn0901-948

M3 - Article

C2 - 11528428

AN - SCOPUS:0034863837

VL - 4

SP - 948

EP - 952

JO - Nature Neuroscience

JF - Nature Neuroscience

SN - 1097-6256

IS - 9

ER -