Pregnancy-Associated Breast Cancer: A Multidisciplinary Approach

Ida Paris, Danilo Di Giorgio, Luisa Carbognin, Giacomo Corrado, Giorgia Garganese, Gianluca Franceschini, Alejandro Martin Sanchez, Rosa Pasqualina De Vincenzo, Cristina Accetta, Daniela Andreina Terribile, Stefano Magno, Alba Di Leone, Sonia Bove, Riccardo Masetti, Giovanni Scambia

Research output: Contribution to journalReview articlepeer-review


The diagnosis of breast cancer (BC) during pregnancy is uncommon. It has varied among different studies from 1:10,000 to 1:3000 of all pregnancies, with a median age of 33 years. Pregnancy-associated BC represents a challenge in terms of clinical management to guarantee both maternal and fetal security in choosing the right treatment. This situation is complex and requires a multidisciplinary approach, including the surgeon, anesthesiologist, oncologist, radiotherapist, psychologist, and maternal–fetal medicine specialist. In the present review, we examined the management of pregnancy-associated BC, focusing on pathophysiologic background, risk factors, diagnosis, staging procedures, anesthesia, surgical management, and systemic treatment.

Original languageEnglish
Pages (from-to)e120-e127
JournalClinical Breast Cancer
Issue number1
Publication statusPublished - Feb 2021


  • Breast cancer
  • Breastfeeding
  • Diagnosis
  • Pregnancy
  • Treatment of pregnancy-associated breast cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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