Pregnancy in patients with congenital heart disease

P. Presbitero, F. Rabajoli, J. Somerville

Research output: Contribution to journalArticlepeer-review


Pregnancy and delivery in women with congenital heart disease remain inadvisable for patients at high risk due to the following congenital diseases: (1.) Severe left ventricular outflow tract obstruction (increase of pressure gradient); (2.) Eisenmenger syndrome (increase of right to left shunt with worsening of cyanosis and fetal growth retardation); (3.) Marfan syndrome with enlarged aortic root (risk of aortic dissection). In women suffering from cyanotic congenital heart disease the main risk is fetal complications. These are correlated to oxygen saturation and to the type of maternal disease, particularly if a palliative shunt operation has never been performed. Women with left to right shunt, right outflow tract obstruction or previous correction of the disease can go through pregnancy with low risk of mortality. The complications (mainly heart failure and arrhythmias) can be well managed with medical treatment, and the fetal outcome is similar to that in the general population.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalSchweizerische Medizinische Wochenschrift
Issue number7
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Medicine(all)


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