Preliminary analysis of toxicity of benzoxazinones and their metabolites for Folsomia candida

Elena Lo Piparo, Martin Smiesko, Paolo Mazzatorta, Emilio Benfenati, Jacqueline Idinger, Sylvia Blümel

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The overall objective of this study was to explore the toxicity of benzoxazinone allelochemicals and their metabolites to Folsomia candida (Collembola: Isotomidae) (Willem, 1902). Experimental tests showed transformation products to have more pronounced toxicity than parent compounds. The underlying relationship between the chemical structure and toxicity was then studied using three-dimensional QSAR approaches, and results highlighted the role of the steric contribution.

Original languageEnglish
Pages (from-to)1099-1104
Number of pages6
JournalJournal of Agricultural and Food Chemistry
Volume54
Issue number4
DOIs
Publication statusPublished - Feb 22 2006

Fingerprint

Benzoxazines
benzoxazinoids
Folsomia candida
Quantitative Structure-Activity Relationship
Candida
Pheromones
Metabolites
Toxicity
metabolites
toxicity
Isotomidae
quantitative structure-activity relationships
allelochemicals
Collembola
chemical structure
testing

Keywords

  • 3D QSAR
  • Benzoxazinones
  • CoMFA
  • Folsomia candida
  • LC

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Food Science
  • Chemistry (miscellaneous)

Cite this

Preliminary analysis of toxicity of benzoxazinones and their metabolites for Folsomia candida. / Lo Piparo, Elena; Smiesko, Martin; Mazzatorta, Paolo; Benfenati, Emilio; Idinger, Jacqueline; Blümel, Sylvia.

In: Journal of Agricultural and Food Chemistry, Vol. 54, No. 4, 22.02.2006, p. 1099-1104.

Research output: Contribution to journalArticle

Lo Piparo, Elena ; Smiesko, Martin ; Mazzatorta, Paolo ; Benfenati, Emilio ; Idinger, Jacqueline ; Blümel, Sylvia. / Preliminary analysis of toxicity of benzoxazinones and their metabolites for Folsomia candida. In: Journal of Agricultural and Food Chemistry. 2006 ; Vol. 54, No. 4. pp. 1099-1104.
@article{0fd18aa3aba447e2a217c56cc2c258e6,
title = "Preliminary analysis of toxicity of benzoxazinones and their metabolites for Folsomia candida",
abstract = "The overall objective of this study was to explore the toxicity of benzoxazinone allelochemicals and their metabolites to Folsomia candida (Collembola: Isotomidae) (Willem, 1902). Experimental tests showed transformation products to have more pronounced toxicity than parent compounds. The underlying relationship between the chemical structure and toxicity was then studied using three-dimensional QSAR approaches, and results highlighted the role of the steric contribution.",
keywords = "3D QSAR, Benzoxazinones, CoMFA, Folsomia candida, LC",
author = "{Lo Piparo}, Elena and Martin Smiesko and Paolo Mazzatorta and Emilio Benfenati and Jacqueline Idinger and Sylvia Bl{\"u}mel",
year = "2006",
month = "2",
day = "22",
doi = "10.1021/jf050916v",
language = "English",
volume = "54",
pages = "1099--1104",
journal = "Journal of Agricultural and Food Chemistry",
issn = "0021-8561",
publisher = "American Chemical Society",
number = "4",

}

TY - JOUR

T1 - Preliminary analysis of toxicity of benzoxazinones and their metabolites for Folsomia candida

AU - Lo Piparo, Elena

AU - Smiesko, Martin

AU - Mazzatorta, Paolo

AU - Benfenati, Emilio

AU - Idinger, Jacqueline

AU - Blümel, Sylvia

PY - 2006/2/22

Y1 - 2006/2/22

N2 - The overall objective of this study was to explore the toxicity of benzoxazinone allelochemicals and their metabolites to Folsomia candida (Collembola: Isotomidae) (Willem, 1902). Experimental tests showed transformation products to have more pronounced toxicity than parent compounds. The underlying relationship between the chemical structure and toxicity was then studied using three-dimensional QSAR approaches, and results highlighted the role of the steric contribution.

AB - The overall objective of this study was to explore the toxicity of benzoxazinone allelochemicals and their metabolites to Folsomia candida (Collembola: Isotomidae) (Willem, 1902). Experimental tests showed transformation products to have more pronounced toxicity than parent compounds. The underlying relationship between the chemical structure and toxicity was then studied using three-dimensional QSAR approaches, and results highlighted the role of the steric contribution.

KW - 3D QSAR

KW - Benzoxazinones

KW - CoMFA

KW - Folsomia candida

KW - LC

UR - http://www.scopus.com/inward/record.url?scp=33644862379&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33644862379&partnerID=8YFLogxK

U2 - 10.1021/jf050916v

DO - 10.1021/jf050916v

M3 - Article

VL - 54

SP - 1099

EP - 1104

JO - Journal of Agricultural and Food Chemistry

JF - Journal of Agricultural and Food Chemistry

SN - 0021-8561

IS - 4

ER -