Preliminary characterization in mice of the effect of isoprinosine on the immune system

A. Vecchi, M. Sironi, F. Spreafico

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Abstract

A preliminary characterization of the immunomodulatory activity of isoprinosine in mice was conducted in both normal and tumor-bearing mice. Under the experimental conditions employed, isoprinosine given i.p. and orally was found to possess some immunomodulatory capacity in various model systems. The compound appeared to preferentially influence T- but not B-cell responses; it did not apparently influence the functional capacity of macrophages, K cells, and NK cells.

Original languageEnglish
Pages (from-to)1975-1979
Number of pages5
JournalCancer Treatment Reports
Volume62
Issue number11
Publication statusPublished - 1978

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Inosine Pranobex
Immune System
Natural Killer Cells
B-Lymphocytes
Macrophages
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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Preliminary characterization in mice of the effect of isoprinosine on the immune system. / Vecchi, A.; Sironi, M.; Spreafico, F.

In: Cancer Treatment Reports, Vol. 62, No. 11, 1978, p. 1975-1979.

Research output: Contribution to journalArticle

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