Oral photochemotherapy was employed to 44 patients with histologically confirmed mycosis fungoides divided into stages according to Van Scott. 8-methoxypsoralen was used as the photosensitizing substance. Longwavelength ultraviolet light was provided by a Waldmann 3001 system. The classic PUVA scheme was used for both the attack and the maintenance stages. A clinical improvement assessed at 80-100% was noted in 95.3% of patients in stages I and II taken as a whole. The mean total dose was of 54.02 J/cm2 for stage I patients and 56.2 J/cm2 for stage II. Complete remission at the last check-up was observed in 56.5% of stage I and 42.1% of stage II patients. Recurrence 2-6 months after the suspension of the treatment was noted in 17.4% an 47.4% respectively. There were no side-effects of any consequence. These preliminary results are compared with those in the literature. The role of photochemotherapy in the management of mycosis fungoides is also discussed.
|Translated title of the contribution||Preliminary results with photochemotherapy in the treatment of mycosis fungoides|
|Number of pages||7|
|Journal||Giornale Italiano di Dermatologia e Venereologia|
|Publication status||Published - 1985|
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