FOTOCHEMIOTERAPIA DELLA MICOSI FUNGOIDE. RISULTATI PRELIMINARI DELLA NOSTRA CASISTICA

Translated title of the contribution: Preliminary results with photochemotherapy in the treatment of mycosis fungoides

M. Caccialanza, D. Contini, M. Alessi, L. Brambilla, V. Boneschi

Research output: Contribution to journalArticlepeer-review

Abstract

Oral photochemotherapy was employed to 44 patients with histologically confirmed mycosis fungoides divided into stages according to Van Scott. 8-methoxypsoralen was used as the photosensitizing substance. Longwavelength ultraviolet light was provided by a Waldmann 3001 system. The classic PUVA scheme was used for both the attack and the maintenance stages. A clinical improvement assessed at 80-100% was noted in 95.3% of patients in stages I and II taken as a whole. The mean total dose was of 54.02 J/cm2 for stage I patients and 56.2 J/cm2 for stage II. Complete remission at the last check-up was observed in 56.5% of stage I and 42.1% of stage II patients. Recurrence 2-6 months after the suspension of the treatment was noted in 17.4% an 47.4% respectively. There were no side-effects of any consequence. These preliminary results are compared with those in the literature. The role of photochemotherapy in the management of mycosis fungoides is also discussed.

Translated title of the contributionPreliminary results with photochemotherapy in the treatment of mycosis fungoides
Original languageItalian
Pages (from-to)91-97
Number of pages7
JournalGiornale Italiano di Dermatologia e Venereologia
Volume120
Issue number1
Publication statusPublished - 1985

ASJC Scopus subject areas

  • Dermatology

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