15 demented patients aged 56-71 years, who underwent a therapeutic trial with DL or L acetyl carnitine for a period ranging from 1 to 12 months were studied. A number of clinical and electrophysiological parameters (P 300) were evaluated before and after the trial to assess the effect of the drug. In about half of our patients an improvement in intellectual performance and behavior was observed, corresponding to a decrease of P 300 latencies. The mechanisms of action of acetyl carnitine in dementia are discussed.
|Translated title of the contribution||Preliminary study on acetylcarnitine treatment of patients with mental deterioration|
|Number of pages||13|
|Journal||Rivista di Neurologia|
|Publication status||Published - 1982|
ASJC Scopus subject areas
- Clinical Neurology