Prenatal diagnosis of the fragile-X in male monozygotic twins: Discordant expression of the fragile site in amniocytes

M. Rocchi, V. Pecile, N. Archidiacono, G. Monni, Y. Dumez, G. Filippi

Research output: Contribution to journalArticle

Abstract

A prenatal diagnosis of the fragile-X syndrome in monozygotic male twins is reported. The expression of the fragile site was discordant in amniotic cells. Fetal blood and, after therapeutic abortion, skin fibroblasts were positive in both fetuses. Our data suggest that great care should be taken when using amniocytes for prenatal diagnosis of the fragile-X syndrome.

Original languageEnglish
Pages (from-to)229-231
Number of pages3
JournalPrenatal Diagnosis
Volume5
Issue number3
DOIs
Publication statusPublished - 1985

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Fragile X Syndrome
Monozygotic Twins
Prenatal Diagnosis
Therapeutic Abortion
Fetal Blood
Fetus
Fibroblasts
Skin

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynaecology

Cite this

Prenatal diagnosis of the fragile-X in male monozygotic twins : Discordant expression of the fragile site in amniocytes. / Rocchi, M.; Pecile, V.; Archidiacono, N.; Monni, G.; Dumez, Y.; Filippi, G.

In: Prenatal Diagnosis, Vol. 5, No. 3, 1985, p. 229-231.

Research output: Contribution to journalArticle

Rocchi, M. ; Pecile, V. ; Archidiacono, N. ; Monni, G. ; Dumez, Y. ; Filippi, G. / Prenatal diagnosis of the fragile-X in male monozygotic twins : Discordant expression of the fragile site in amniocytes. In: Prenatal Diagnosis. 1985 ; Vol. 5, No. 3. pp. 229-231.
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