Five pregnancies at risk for X-linked retinitis pigmentosa (RP) have been monitored by first-trimester prenatal diagnosis using DNA markers flanking the RP2 and RP3 loci. Three affected and two unaffected fetuses, including a female carrying a wild-type genotype, were predicted on the basis of marker segregation and estimation of the recombination fraction.
|Number of pages||5|
|Publication status||Published - 1994|
- DNA probes
- X-linked retinitis pigmentosa
ASJC Scopus subject areas
- Obstetrics and Gynaecology