Prenatal evaluation of congenital heart disease in high-risk pregnancies

A. Giancotti, F. Torcia, G. Giampa, G. Gallow, F. Gallow, L. Donati, D. De Santo

Research output: Contribution to journalArticlepeer-review


The authors report their experience of echocardiography performed on a group of 736 pregnancies with specific risk-factors for congenital heart disease (CHD). The aim of the study was to evaluate the influence of specific risk-factors (established through the genetic counselling) in detecting fetal cardiac anomalies and diagnostic accuracy of extended fetal echocardiographic examination in high-risk pregnancies. Twenty-seven heart defects were observed (3.6%), of these 24 were detected at ultrasound. Specificity and sensitivity were 99% and 90% respectively. These results suggest the importance of an early detection of pregnancies at increased risk for CHD and confirm the good diagnostic accuracy of a multiple cardiac examination.

Original languageEnglish
Pages (from-to)225-229
Number of pages5
JournalClinical and Experimental Obstetrics and Gynecology
Issue number3
Publication statusPublished - 1995


  • Congenital heart disease
  • Fetal echocardiography
  • High risk pregnancies

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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