Prenatal ultrasound detection of bilateral focal polymicrogyria

Linei Augusta Brolini Delle Urban, Andrea Righini, Mariangela Rustico, Fabio Triulzi, Umberto Nicolini

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Prenatal diagnosis by ultrasound of fetal polymicrogyria has been reported only once. Methods: We describe an additional case of polymicrogyria in a fetus from a monozygotic twin pair, probably the consequence of twin-to-twin transfusion syndrome. Results: On ultrasound, there were bilateral cortical hyperechogenic spots, and prenatal magnetic resonance imaging demonstrated the typical features of bilateral focal polymicrogyria. Conclusion: Polymicrogyria can be considered in the differential diagnosis of hyperechogenic brain lesions on fetal ultrasound. We also confirm the risk of brain damage in monochorionic twins pregnancies and the likely hypoxic-ischemic etiology of polymicrogyria.

Original languageEnglish
Pages (from-to)808-811
Number of pages4
JournalPrenatal Diagnosis
Volume24
Issue number10
DOIs
Publication statusPublished - Oct 2004

Keywords

  • Fetal magnetic resonance imaging
  • Migration anomalies
  • Polymicrogyria
  • Prenatal ultrasound
  • Twin fetuses

ASJC Scopus subject areas

  • Genetics(clinical)
  • Obstetrics and Gynaecology

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