Preoperative management and surgical therapy in complicated acute infective endocarditis

a 5-year experience

V. Arena, P. S. Gerometta, G. Pompilio, M. Zanobini, A. Parolari, C. Antona, G. L. Polvani, G. Susini, P. Biglioli

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Twenty-five patients underwent early and elective valve replacement for infective endocarditis during a 5-year period between April 1985 and March 1991. Indications for urgent surgical intervention performed at a mean 32 (range 6-47) days after admission were intractable heart failure, systemic emboli, septic multiorgan failure and the presence of vegetations. Indication for elective surgery was persistent (mean 42 (range 17-56) days) infection after appropriate antibiotic therapy. Twenty patients (80%) had a native valve endocarditis; five (20%) had prosthetic valve involvement. A total of 30 valvular prostheses were implanted: 22 (73.3%) were aortic (21 mechanical and one biological); eight (26.7%) were mitral (all mechanical). All unstable patients referred were treated before surgery in the intensive care unit and subjected to blood ultrafiltration to restore satisfactory circulatory parameters. No patient underwent cardiac catheterization; all patients were operated upon on the basis of echocardiographic data alone. One patient (4%) died during hospitalization; two (8%) died later at 48 and 12 months after the first intervention. The reoperation rate was 12%. After a mean follow-up of 49 (range 1-71) months, 21 of the survivors (95%) were in New York Heart Association functional class I or II; the actuarial 5-year survival rate was 87%. Precise preoperative assessment of early operative indications and timely association of medical therapy in unstable patients could represent a step forward in the treatment of acute infective endocarditis.

Original languageEnglish
Pages (from-to)419-425
Number of pages7
JournalCardiovascular Surgery
Volume1
Issue number4
Publication statusPublished - Aug 1993

Fingerprint

Endocarditis
Therapeutics
Ultrafiltration
Cardiac Catheterization
Embolism
Reoperation
Prostheses and Implants
Intensive Care Units
Survivors
Hospitalization
Survival Rate
Heart Failure
Anti-Bacterial Agents
Infection

Keywords

  • complications
  • infective endocarditis
  • risk stratification
  • surgery

ASJC Scopus subject areas

  • Surgery
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Preoperative management and surgical therapy in complicated acute infective endocarditis : a 5-year experience. / Arena, V.; Gerometta, P. S.; Pompilio, G.; Zanobini, M.; Parolari, A.; Antona, C.; Polvani, G. L.; Susini, G.; Biglioli, P.

In: Cardiovascular Surgery, Vol. 1, No. 4, 08.1993, p. 419-425.

Research output: Contribution to journalArticle

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