Preoperative multiparametric MRI of the prostate for the prediction of lymph node metastases in prostate cancer patients treated with extended pelvic lymph node dissection

G Brembilla, P Dell'Oglio, Armando Stabile, A Ambrosi, G Cristel, L Brunetti, Anna Damascelli, M Freschi, A Esposito, A Briganti, F Montorsi, A Del Maschio, F De Cobelli

Research output: Contribution to journalArticle

Abstract

OBJECTIVES: To assess the role of preoperative multiparametric MRI (mpMRI) of the prostate in the prediction of nodal metastases in patients treated with radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND). METHODS: We retrospectively analyzed 101 patients who underwent both preoperative mpMRI of the prostate and RP with ePLND at our institution. For each patient, complete preoperative clinical data and tumour characteristics at mpMRI were recorded. Final histopathologic stage was considered the standard of reference. Univariate and multivariate logistic regression analyses were performed. RESULTS: Nodal metastases were found in 23/101 (22.8%) patients. At univariate analyses, all clinical and radiological parameters were significantly associated to nodal invasion (all p
Original languageEnglish
Pages (from-to)1969-1976
Number of pages8
JournalEuropean Radiology
Volume28
Issue number5
DOIs
Publication statusPublished - 2018

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