Preparation of a new nerve guide from a poly(l-lactide-co-6-caprolactone)

Gabriele Perego, Gian Domenico Cella, NicolòNicoli Aldini, Milena Fini, Roberto Giardino

Research output: Contribution to journalArticle

Abstract

A copolymer of l-lactide and 6-caprolactone (50:50, w/w) was synthesized and characterized. The thermal behaviour of this material did not show any crystallinity for several months; only after more than 1 yr of aging at room temperature and, particularly, in the in vitro degradation tests did it partially crystallize. The values of tensile strength, percent elongation at break and elastic modulus were, respectively, 25 MPa, 490% and 3 MPa. Transparent, elastic nerve guides having inner diameter of 1.3 mm and wall thickness of 175 μm were prepared.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalBiomaterials
Volume15
Issue number3
DOIs
Publication statusPublished - 1994

Keywords

  • characterization
  • degradation
  • mechanical properties
  • Nerve guide
  • polylactides

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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