Abstract
Urinary colony stimulating factor (CSF) from human leukemic urine is retained on prophylamine-agarose hydrophibic chromatography; about 70% of the total activity is eluted by the addition of 1 M NaCl with significant increase in specific activity. Incomplete binding of urinary CSF to this resin further confirms that biological activity is a heterogeneous pool of different molecular species. Analysis of the macro- and microscopic composition of colonies indicates that CSF resulting from this purification step maintains the ability to stimulate both granulocytic and macrophage progenitors.
Original language | English |
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Pages (from-to) | 178-181 |
Number of pages | 4 |
Journal | Biomedicine Express |
Volume | 33 |
Issue number | 6 |
Publication status | Published - 1980 |
ASJC Scopus subject areas
- Medicine(all)