Preparing for phase II/III HIV vaccine trials in Africa

Eftyhia Vardas, Stefano Buttò, Richard Glashoff, Mauro S. Malnati, Guido Poli, Mario Clerici

Research output: Contribution to journalArticle

Abstract

Before performing phase II/III clinical trials in Africa, preliminary studies, including assessment and building up of clinical and laboratory infrastructures, estimates of human immunodeficiency virus incidence, investigation of the background immune response, and evaluation of the cross-clade immune response, need to be done. Plans and ongoing work in the context of the AIDS Vaccine Integrated Project and some preliminary data are presented.

Original languageEnglish
Pages (from-to)1436-1444
Number of pages9
JournalMicrobes and Infection
Volume7
Issue number14
DOIs
Publication statusPublished - Nov 2005

Keywords

  • Cross-reactivity
  • Sub-Saharan Africa
  • Vaccine

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

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