Preproenkephalin mRNA expression in nucleus caudalis neurons is enhanced by trigeminal stimulation

Toshikazu Nishimori, M. Gabriella Buzzi, Michael A. Moskowitz, George R. Uhl

Research output: Contribution to journalArticle

Abstract

Electrical stimulation of trigeminal afferents increases expression of preproenkephalin mRNA in neurons of laminae I and II of the trigeminal nucleus caudalis in animals sacrificed 6 hours after the end of stimulation. More neurons express, and positive cells express at higher levels. These neurons thus express the mRNA corresponding to a major pain-modulating neurotransmitter gene with significant input-related plasticity.

Original languageEnglish
Pages (from-to)203-210
Number of pages8
JournalMolecular Brain Research
Volume6
Issue number2-3
DOIs
Publication statusPublished - 1989

Fingerprint

Neurons
Messenger RNA
Substantia Gelatinosa
Trigeminal Nuclei
Electric Stimulation
Neurotransmitter Agents
Pain
Genes
preproenkephalin
Spinal Cord Dorsal Horn

Keywords

  • Nucleus caudalis
  • Preproenkephalin mRNA
  • Trigeminal afferent

ASJC Scopus subject areas

  • Molecular Biology
  • Cellular and Molecular Neuroscience

Cite this

Preproenkephalin mRNA expression in nucleus caudalis neurons is enhanced by trigeminal stimulation. / Nishimori, Toshikazu; Buzzi, M. Gabriella; Moskowitz, Michael A.; Uhl, George R.

In: Molecular Brain Research, Vol. 6, No. 2-3, 1989, p. 203-210.

Research output: Contribution to journalArticle

Nishimori, Toshikazu ; Buzzi, M. Gabriella ; Moskowitz, Michael A. ; Uhl, George R. / Preproenkephalin mRNA expression in nucleus caudalis neurons is enhanced by trigeminal stimulation. In: Molecular Brain Research. 1989 ; Vol. 6, No. 2-3. pp. 203-210.
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