Presence of N-methyl-D-aspartate-like and kainate-like and kainate-like activities in bovine brain

Alberto Luini; Ora Goldberg; Vivian I. Teichberg

doi:10.1016/0014-5793(83)80750-9

Presence of N-methyl-D-aspartate-like and kainate-like and kainate-like activities in bovine brain

Alberto Luini, Ora Goldberg, Vivian I. Teichberg

IRCCS SDN

Research output: Contribution to journal › Article › peer-review

Abstract

Searching for the natural ligands interacting with brain excitatory amino acid receptors, we have isolated from cow brain a low-M_r ampholyte fraction containing molecules with excitatory properties similar to those of N-methyl-D-aspartate and kainate, which cannot be accounted for by any of the known brain excitants. This finding supports the hypothesis of the existence of excitatory neurotransmitters other than L-glutamate and L-aspartate.

Original language	English
Pages (from-to)	153-157
Number of pages	5
Journal	FEBS Letters
Volume	161
Issue number	1
DOIs	https://doi.org/10.1016/0014-5793(83)80750-9
Publication status	Published - Sep 5 1983

Keywords

Brain endogenous ligand
Excitatory amino acid
Putative excitatory neurotransmitter
Receptor

ASJC Scopus subject areas

Biochemistry
Biophysics
Molecular Biology

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10.1016/0014-5793(83)80750-9

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Presence of N-methyl-D-aspartate-like and kainate-like and kainate-like activities in bovine brain

Abstract

Keywords

ASJC Scopus subject areas

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