Evidence is presented which shows that a Schwannoma removed from a 70-year-old woman contained a high level of NGF and also expressed NGF-r in addition to two other specific Schwann cell markers, S-100 and GFAP. A cell line expressing NGF and NGF-receptors was isolated from this neoplastic tissue. It is suggested that this cell line might provide a useful model for studying mechanisms which regulate NGF and NGF-r.
|Number of pages||5|
|Journal||Clinical Chemistry and Enzymology Communications|
|Publication status||Published - 1993|
- Nerve growth factor (NGF)
ASJC Scopus subject areas
- Clinical Biochemistry