Abstract
The International Breast Cancer Study Group (formerly the Ludwig Group) has conducted nine clinical trials since 1978 (see the Appendix for participants and authors). Biologic hypotheses related to the combined use of chemotherapy and endocrine therapy in women with operable breast cancer were tested. Questions of timing of chemotherapy with respect to tumor surgery and late introduction of chemotherapy were also evaluated. On-going and future trials continue in this tradition to investigate combinations of available endocrine therapies and cytotoxic agents.
| Original language | English |
|---|---|
| Pages (from-to) | 1139-1149 |
| Number of pages | 11 |
| Journal | Cancer |
| Volume | 74 |
| Issue number | 3 |
| Publication status | Published - 1994 |
Keywords
- adjuvant therapy
- breast cancer
- chemoendocrine therapy
- chemotherapy
- clinical trials
- cyclophosphamide-methotrexate-5- fluorouracil
- endocrine therapy
- tamoxifen
ASJC Scopus subject areas
- Cancer Research
- Oncology
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Cite this
Goldhirsch, A., Gelber, R. D., Castiglione, M., Price, K. N., Rudenstam -, C. M., Lindtner, J., Collins, J., Senn, H. J., Brunner, K. W., Galligioni, E., Cavalli, F., Gudgeon, A., Cortes-Funes, H., Tattersall, M., Marini, G., Byrne, M., Snyder, R., Forbes, J. F., Hurny, C., & Coates, A. (1994). Present and future projects of the International Breast Cancer Study Group. Cancer, 74(3), 1139-1149.