Presentation and clinical outcomes of choledochal cysts in children and adults

A multi-institutional analysis

Kevin C. Soares, Yuhree Kim, Gaya Spolverato, Shishir Maithel, Todd W. Bauer, Hugo Marques, Mafalda Sobral, Maria Knoblich, Thuy Tran, Luca Aldrighetti, Nicolas Jabbour, George A. Poultsides, T. Clark Gamblin, Timothy M. Pawlik

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

IMPORTANCE: Choledochal cysts (CCs) are rare, with risk of infection and cancer. OBJECTIVE: To characterize the natural history, management, and long-term implications of CC disease. DESIGN, SETTING, AND PARTICIPANTS A total of 394 patients who underwent resection of a CC between January 1, 1972, and April 11, 2014, were identified from an international multi-institutional database. Patients were followed up through September 27, 2014. Clinicopathologic characteristics, operative details, and outcome data were analyzed from May 1, 2014, to October 14, 2014. INTERVENTION Resection of CC. MAINOUTCOMESANDMEASURES Management, morbidity, and overall survival. RESULTS: Among 394 patients, there were 135 children (34.3%) and 318 women (80.7%). Adults were more likely to present with abdominal pain (71.8% vs 40.7%; P

Original languageEnglish
Pages (from-to)577-584
Number of pages8
JournalJAMA Surgery
Volume150
Issue number6
DOIs
Publication statusPublished - Jun 1 2015

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Choledochal Cyst
Natural History
Abdominal Pain
Databases
Morbidity
Survival
Infection
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

Cite this

Soares, K. C., Kim, Y., Spolverato, G., Maithel, S., Bauer, T. W., Marques, H., ... Pawlik, T. M. (2015). Presentation and clinical outcomes of choledochal cysts in children and adults: A multi-institutional analysis. JAMA Surgery, 150(6), 577-584. https://doi.org/10.1001/jamasurg.2015.0226

Presentation and clinical outcomes of choledochal cysts in children and adults : A multi-institutional analysis. / Soares, Kevin C.; Kim, Yuhree; Spolverato, Gaya; Maithel, Shishir; Bauer, Todd W.; Marques, Hugo; Sobral, Mafalda; Knoblich, Maria; Tran, Thuy; Aldrighetti, Luca; Jabbour, Nicolas; Poultsides, George A.; Gamblin, T. Clark; Pawlik, Timothy M.

In: JAMA Surgery, Vol. 150, No. 6, 01.06.2015, p. 577-584.

Research output: Contribution to journalArticle

Soares, KC, Kim, Y, Spolverato, G, Maithel, S, Bauer, TW, Marques, H, Sobral, M, Knoblich, M, Tran, T, Aldrighetti, L, Jabbour, N, Poultsides, GA, Gamblin, TC & Pawlik, TM 2015, 'Presentation and clinical outcomes of choledochal cysts in children and adults: A multi-institutional analysis', JAMA Surgery, vol. 150, no. 6, pp. 577-584. https://doi.org/10.1001/jamasurg.2015.0226
Soares, Kevin C. ; Kim, Yuhree ; Spolverato, Gaya ; Maithel, Shishir ; Bauer, Todd W. ; Marques, Hugo ; Sobral, Mafalda ; Knoblich, Maria ; Tran, Thuy ; Aldrighetti, Luca ; Jabbour, Nicolas ; Poultsides, George A. ; Gamblin, T. Clark ; Pawlik, Timothy M. / Presentation and clinical outcomes of choledochal cysts in children and adults : A multi-institutional analysis. In: JAMA Surgery. 2015 ; Vol. 150, No. 6. pp. 577-584.
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