Presentation and management of acute coronary syndromes among adult persons with haemophilia: Results of an international, retrospective, 10-year survey

P. F. Fogarty, M. E. Mancuso, R. Kasthuri, C. Bidlingmaier, M. Chitlur, K. Gomez, P. A. Holme, P. James, R. Kruse-Jarres, J. Mahlangu, M. E. Mingot-Castellano, A. Soni

Research output: Contribution to journalArticle

Abstract

Sparse data are available on presentation and management of acute coronary syndromes (ACS), including unstable angina and non-ST- and ST-elevation myocardial infarction, among persons with haemophilia (PWH). The aim of this study was to determine demographics, bleeding disorder characteristics, cardiovascular risk factors (CRFs), interventions, haemostatic protocol, revascularization outcomes and complications among PWH with ACS. Members of an international consortium comprising >2000 adult PWH retrospectively completed case report forms for episodes of ACS in a >10-year follow-up period (2003-2013). Twenty ACS episodes occurred among 19 patients [rate, 0.8% (95% CI 0.4, 1.2)]. Seven patients (37%) were aged

Original languageEnglish
Pages (from-to)589-597
Number of pages9
JournalHaemophilia
Volume21
Issue number5
DOIs
Publication statusPublished - Sep 1 2015

Keywords

  • Acute coronary syndrome
  • Antiplatelet therapy
  • Cardiovascular disease
  • Haemophilia
  • Myocardial infarction
  • Stent

ASJC Scopus subject areas

  • Hematology
  • Genetics(clinical)

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    Fogarty, P. F., Mancuso, M. E., Kasthuri, R., Bidlingmaier, C., Chitlur, M., Gomez, K., Holme, P. A., James, P., Kruse-Jarres, R., Mahlangu, J., Mingot-Castellano, M. E., & Soni, A. (2015). Presentation and management of acute coronary syndromes among adult persons with haemophilia: Results of an international, retrospective, 10-year survey. Haemophilia, 21(5), 589-597. https://doi.org/10.1111/hae.12652