Abstract
Objective: Few data are available on the surgical results in patients with incidentally discovered nonfunctioning pituitary adenoma (NFPA). We investigated the efficacy and safety of surgery in patients with incidentally discovered NFPA. Design: Retrospective analysis of prospectively recorded outcomes. Methods: From 1990 to 2011, of 804 consecutive patients undergoing surgery for NFPA, 212 cases had an incidentally discovered tumor (26.4%). Among them, 117 patients were asymptomatic, while 95 had some visual and/or hormonal deficit. The main outcome of the study was to evaluate the frequency of radical resection as judged on the first postoperative neuroimaging study and detection of recurring disease during long-term follow-up. Results: Postoperative residual tumor was detected in 8.9% of patients with asymptomatic incidentalomas as compared with 31.2% of patients with symptomatic incidentalomas (P
| Original language | English |
|---|---|
| Pages (from-to) | 735-742 |
| Number of pages | 8 |
| Journal | European Journal of Endocrinology |
| Volume | 169 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2013 |
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ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Medicine(all)
Cite this
Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas : Evidence for a better outcome independently of other patients' characteristics. / Losa, Marco; Donofrio, Carmine A.; Barzaghi, Raffaella; Mortini, Pietro.
In: European Journal of Endocrinology, Vol. 169, No. 6, 2013, p. 735-742.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Presentation and surgical results of incidentally discovered nonfunctioning pituitary adenomas
T2 - Evidence for a better outcome independently of other patients' characteristics
AU - Losa, Marco
AU - Donofrio, Carmine A.
AU - Barzaghi, Raffaella
AU - Mortini, Pietro
PY - 2013
Y1 - 2013
N2 - Objective: Few data are available on the surgical results in patients with incidentally discovered nonfunctioning pituitary adenoma (NFPA). We investigated the efficacy and safety of surgery in patients with incidentally discovered NFPA. Design: Retrospective analysis of prospectively recorded outcomes. Methods: From 1990 to 2011, of 804 consecutive patients undergoing surgery for NFPA, 212 cases had an incidentally discovered tumor (26.4%). Among them, 117 patients were asymptomatic, while 95 had some visual and/or hormonal deficit. The main outcome of the study was to evaluate the frequency of radical resection as judged on the first postoperative neuroimaging study and detection of recurring disease during long-term follow-up. Results: Postoperative residual tumor was detected in 8.9% of patients with asymptomatic incidentalomas as compared with 31.2% of patients with symptomatic incidentalomas (P
AB - Objective: Few data are available on the surgical results in patients with incidentally discovered nonfunctioning pituitary adenoma (NFPA). We investigated the efficacy and safety of surgery in patients with incidentally discovered NFPA. Design: Retrospective analysis of prospectively recorded outcomes. Methods: From 1990 to 2011, of 804 consecutive patients undergoing surgery for NFPA, 212 cases had an incidentally discovered tumor (26.4%). Among them, 117 patients were asymptomatic, while 95 had some visual and/or hormonal deficit. The main outcome of the study was to evaluate the frequency of radical resection as judged on the first postoperative neuroimaging study and detection of recurring disease during long-term follow-up. Results: Postoperative residual tumor was detected in 8.9% of patients with asymptomatic incidentalomas as compared with 31.2% of patients with symptomatic incidentalomas (P
UR - http://www.scopus.com/inward/record.url?scp=84888273409&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84888273409&partnerID=8YFLogxK
U2 - 10.1530/EJE-13-0515
DO - 10.1530/EJE-13-0515
M3 - Article
C2 - 23999643
AN - SCOPUS:84888273409
VL - 169
SP - 735
EP - 742
JO - European Journal of Endocrinology
JF - European Journal of Endocrinology
SN - 0804-4643
IS - 6
ER -