Abstract
Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N=44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N=37) or with a major depression-like episode (MSD-MDL; N=13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p=.038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
| Original language | English |
|---|---|
| Pages (from-to) | 571-587 |
| Number of pages | 17 |
| Journal | Clinical Neuropsychologist |
| Volume | 26 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - May 1 2012 |
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Keywords
- Beck Depression Inventory
- Depression
- Multiple sclerosis
ASJC Scopus subject areas
- Psychiatry and Mental health
- Neuropsychology and Physiological Psychology
- Clinical Psychology
- Arts and Humanities (miscellaneous)
- Developmental and Educational Psychology
- Medicine(all)
Cite this
Presentation and validation of the multiple sclerosis depression rating scale : A test specifically devised to investigate affective disorders in multiple sclerosis patients. / Quaranta, Davide; Marra, Camillo; Zinno, Massimiliano; Patanella, Agata Katia; Messina, Maria Josè; Piccininni, Chiara; Batocchi, Anna Paola; Gainotti, Guido.
In: Clinical Neuropsychologist, Vol. 26, No. 4, 01.05.2012, p. 571-587.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Presentation and validation of the multiple sclerosis depression rating scale
T2 - A test specifically devised to investigate affective disorders in multiple sclerosis patients
AU - Quaranta, Davide
AU - Marra, Camillo
AU - Zinno, Massimiliano
AU - Patanella, Agata Katia
AU - Messina, Maria Josè
AU - Piccininni, Chiara
AU - Batocchi, Anna Paola
AU - Gainotti, Guido
PY - 2012/5/1
Y1 - 2012/5/1
N2 - Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N=44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N=37) or with a major depression-like episode (MSD-MDL; N=13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p=.038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
AB - Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N=44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N=37) or with a major depression-like episode (MSD-MDL; N=13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p=.038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
KW - Beck Depression Inventory
KW - Depression
KW - Multiple sclerosis
UR - http://www.scopus.com/inward/record.url?scp=84861512136&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861512136&partnerID=8YFLogxK
U2 - 10.1080/13854046.2012.668220
DO - 10.1080/13854046.2012.668220
M3 - Article
C2 - 22428778
AN - SCOPUS:84861512136
VL - 26
SP - 571
EP - 587
JO - Clinical Neuropsychologist
JF - Clinical Neuropsychologist
SN - 1385-4046
IS - 4
ER -