Abstract
Accurate diagnosis of depression in patients affected by MS is important, as it may be a cause of reduced quality of life and increased suicide risk. We present a new scale, the Multiple Sclerosis Depression Rating Scale (MSDRS), and assess its diagnostic accuracy in comparison to the Beck Depression Inventory (BDI). A total of 94 MS participants were classified as non-depressed (N=44) or affected by mood disorder associated to MS with depressive manifestations (MSD-MDDM; N=37) or with a major depression-like episode (MSD-MDL; N=13). Each participant underwent a psychiatric interview, MSDRS, and BDI; diagnostic accuracy was evaluated using area under the ROC curve (AROC). The diagnostic accuracy of MSDRS and BDI was comparable when diagnosing both MSD-MDDM and MSD-MDL (AROC respectively 0.8998 and 0.8659); the MSDRS showed higher accuracy for the diagnosis of MSD-MDL (AROC respectively 0.9278 and 0.8314; p=.038). The MSDRS may be a reliable tool for the diagnosis of depression in MS.
Original language | English |
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Pages (from-to) | 571-587 |
Number of pages | 17 |
Journal | Clinical Neuropsychologist |
Volume | 26 |
Issue number | 4 |
DOIs | |
Publication status | Published - May 1 2012 |
Keywords
- Beck Depression Inventory
- Depression
- Multiple sclerosis
ASJC Scopus subject areas
- Psychiatry and Mental health
- Neuropsychology and Physiological Psychology
- Clinical Psychology
- Arts and Humanities (miscellaneous)
- Developmental and Educational Psychology
- Medicine(all)