Preserved Postoperative Penile Size Correlates Well with Maintained Erectile Function after Bilateral Nerve-Sparing Radical Retropubic Prostatectomy

Alberto Briganti, Fabio Fabbri, Andrea Salonia, Andrea Gallina, Felix K H Chun, Federico Dehò, Giuseppe Zanni, Nazareno Suardi, Pierre I. Karakiewicz, Patrizio Rigatti, Francesco Montorsi

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Objectives: Controversial data on penile length after radical retropubic prostatectomy are available. We hypothesised that postoperative penile size correlates to erectile function following bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). Methods: Thirty-three consecutive patients with a preoperative erectile function domain of the International Index of Erectile Function (IIEF-EF) score indicating full potency (≥26) were prospectively enrolled. All patients underwent BNSRRP performed by one high-volume surgeon. All patients were preoperatively evaluated by IIEF-EF, analysis of comorbidities, physical examination, and penile power colour Doppler ultrasound using intracavernosal injection of prostaglandin E1 (PGE1) 20 μg plus audiovisual and manual genital stimulation. Penile length and circumference were measured in flaccidity and at maximum erection. Six months postoperative, patients were assessed with the same protocol plus general assessment questions investigating penile structure and function. Statistical analysis was performed with an independent sample t test. Results: Mean patient age was 56.5 yr. We found no difference between the preoperative and the 6-mo postoperative mean IIEF-EF domain score (27.2 vs, 26.7, respectively; p = 0.35). No difference was found in penile colour Doppler evaluation between the preoperative and postoperative periods (all p values ≥0.3). We found no differences in penile length and circumference between the preoperative and postoperative evaluation either in the flaccid or in the erect state. Mean flaccid penile length (cm; preop vs. postop): 13.2 vs. 13 (p = 0.6). Mean flaccid penile circumference (cm; preop vs. postop): 11.1 vs. 11 (p = 0.7). Mean erect penile length (cm; preop vs. postop): 16.8 vs. 16.5 (p = 0.08). Mean erect penile circumference (cm; preop vs. postop): 15.6 vs. 15.3 (p = 0.2). Conclusions: This is the first report on penile changes in flaccidity and at maximum erection after BNSRRP in patients treated by one high-volume surgeon. The postoperative preservation of erectile function positively correlated with the maintenance of penile length following surgery. We found no change in penile size after surgery.

Original languageEnglish
Pages (from-to)702-707
Number of pages6
JournalEuropean Urology
Volume52
Issue number3
DOIs
Publication statusPublished - Sep 2007

Fingerprint

Prostatectomy
Color
Preoperative Period
Doppler Ultrasonography
Alprostadil
Postoperative Period
Physical Examination
Comorbidity
Maintenance
Injections

Keywords

  • Erectile dysfunction
  • Penile size
  • Radical prostatectomy

ASJC Scopus subject areas

  • Urology

Cite this

Preserved Postoperative Penile Size Correlates Well with Maintained Erectile Function after Bilateral Nerve-Sparing Radical Retropubic Prostatectomy. / Briganti, Alberto; Fabbri, Fabio; Salonia, Andrea; Gallina, Andrea; Chun, Felix K H; Dehò, Federico; Zanni, Giuseppe; Suardi, Nazareno; Karakiewicz, Pierre I.; Rigatti, Patrizio; Montorsi, Francesco.

In: European Urology, Vol. 52, No. 3, 09.2007, p. 702-707.

Research output: Contribution to journalArticle

Briganti, Alberto ; Fabbri, Fabio ; Salonia, Andrea ; Gallina, Andrea ; Chun, Felix K H ; Dehò, Federico ; Zanni, Giuseppe ; Suardi, Nazareno ; Karakiewicz, Pierre I. ; Rigatti, Patrizio ; Montorsi, Francesco. / Preserved Postoperative Penile Size Correlates Well with Maintained Erectile Function after Bilateral Nerve-Sparing Radical Retropubic Prostatectomy. In: European Urology. 2007 ; Vol. 52, No. 3. pp. 702-707.
@article{f3e88a5518224f339127ca6cc0b13662,
title = "Preserved Postoperative Penile Size Correlates Well with Maintained Erectile Function after Bilateral Nerve-Sparing Radical Retropubic Prostatectomy",
abstract = "Objectives: Controversial data on penile length after radical retropubic prostatectomy are available. We hypothesised that postoperative penile size correlates to erectile function following bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). Methods: Thirty-three consecutive patients with a preoperative erectile function domain of the International Index of Erectile Function (IIEF-EF) score indicating full potency (≥26) were prospectively enrolled. All patients underwent BNSRRP performed by one high-volume surgeon. All patients were preoperatively evaluated by IIEF-EF, analysis of comorbidities, physical examination, and penile power colour Doppler ultrasound using intracavernosal injection of prostaglandin E1 (PGE1) 20 μg plus audiovisual and manual genital stimulation. Penile length and circumference were measured in flaccidity and at maximum erection. Six months postoperative, patients were assessed with the same protocol plus general assessment questions investigating penile structure and function. Statistical analysis was performed with an independent sample t test. Results: Mean patient age was 56.5 yr. We found no difference between the preoperative and the 6-mo postoperative mean IIEF-EF domain score (27.2 vs, 26.7, respectively; p = 0.35). No difference was found in penile colour Doppler evaluation between the preoperative and postoperative periods (all p values ≥0.3). We found no differences in penile length and circumference between the preoperative and postoperative evaluation either in the flaccid or in the erect state. Mean flaccid penile length (cm; preop vs. postop): 13.2 vs. 13 (p = 0.6). Mean flaccid penile circumference (cm; preop vs. postop): 11.1 vs. 11 (p = 0.7). Mean erect penile length (cm; preop vs. postop): 16.8 vs. 16.5 (p = 0.08). Mean erect penile circumference (cm; preop vs. postop): 15.6 vs. 15.3 (p = 0.2). Conclusions: This is the first report on penile changes in flaccidity and at maximum erection after BNSRRP in patients treated by one high-volume surgeon. The postoperative preservation of erectile function positively correlated with the maintenance of penile length following surgery. We found no change in penile size after surgery.",
keywords = "Erectile dysfunction, Penile size, Radical prostatectomy",
author = "Alberto Briganti and Fabio Fabbri and Andrea Salonia and Andrea Gallina and Chun, {Felix K H} and Federico Deh{\`o} and Giuseppe Zanni and Nazareno Suardi and Karakiewicz, {Pierre I.} and Patrizio Rigatti and Francesco Montorsi",
year = "2007",
month = "9",
doi = "10.1016/j.eururo.2007.03.050",
language = "English",
volume = "52",
pages = "702--707",
journal = "European Urology",
issn = "0302-2838",
publisher = "Elsevier B.V.",
number = "3",

}

TY - JOUR

T1 - Preserved Postoperative Penile Size Correlates Well with Maintained Erectile Function after Bilateral Nerve-Sparing Radical Retropubic Prostatectomy

AU - Briganti, Alberto

AU - Fabbri, Fabio

AU - Salonia, Andrea

AU - Gallina, Andrea

AU - Chun, Felix K H

AU - Dehò, Federico

AU - Zanni, Giuseppe

AU - Suardi, Nazareno

AU - Karakiewicz, Pierre I.

AU - Rigatti, Patrizio

AU - Montorsi, Francesco

PY - 2007/9

Y1 - 2007/9

N2 - Objectives: Controversial data on penile length after radical retropubic prostatectomy are available. We hypothesised that postoperative penile size correlates to erectile function following bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). Methods: Thirty-three consecutive patients with a preoperative erectile function domain of the International Index of Erectile Function (IIEF-EF) score indicating full potency (≥26) were prospectively enrolled. All patients underwent BNSRRP performed by one high-volume surgeon. All patients were preoperatively evaluated by IIEF-EF, analysis of comorbidities, physical examination, and penile power colour Doppler ultrasound using intracavernosal injection of prostaglandin E1 (PGE1) 20 μg plus audiovisual and manual genital stimulation. Penile length and circumference were measured in flaccidity and at maximum erection. Six months postoperative, patients were assessed with the same protocol plus general assessment questions investigating penile structure and function. Statistical analysis was performed with an independent sample t test. Results: Mean patient age was 56.5 yr. We found no difference between the preoperative and the 6-mo postoperative mean IIEF-EF domain score (27.2 vs, 26.7, respectively; p = 0.35). No difference was found in penile colour Doppler evaluation between the preoperative and postoperative periods (all p values ≥0.3). We found no differences in penile length and circumference between the preoperative and postoperative evaluation either in the flaccid or in the erect state. Mean flaccid penile length (cm; preop vs. postop): 13.2 vs. 13 (p = 0.6). Mean flaccid penile circumference (cm; preop vs. postop): 11.1 vs. 11 (p = 0.7). Mean erect penile length (cm; preop vs. postop): 16.8 vs. 16.5 (p = 0.08). Mean erect penile circumference (cm; preop vs. postop): 15.6 vs. 15.3 (p = 0.2). Conclusions: This is the first report on penile changes in flaccidity and at maximum erection after BNSRRP in patients treated by one high-volume surgeon. The postoperative preservation of erectile function positively correlated with the maintenance of penile length following surgery. We found no change in penile size after surgery.

AB - Objectives: Controversial data on penile length after radical retropubic prostatectomy are available. We hypothesised that postoperative penile size correlates to erectile function following bilateral nerve-sparing radical retropubic prostatectomy (BNSRRP). Methods: Thirty-three consecutive patients with a preoperative erectile function domain of the International Index of Erectile Function (IIEF-EF) score indicating full potency (≥26) were prospectively enrolled. All patients underwent BNSRRP performed by one high-volume surgeon. All patients were preoperatively evaluated by IIEF-EF, analysis of comorbidities, physical examination, and penile power colour Doppler ultrasound using intracavernosal injection of prostaglandin E1 (PGE1) 20 μg plus audiovisual and manual genital stimulation. Penile length and circumference were measured in flaccidity and at maximum erection. Six months postoperative, patients were assessed with the same protocol plus general assessment questions investigating penile structure and function. Statistical analysis was performed with an independent sample t test. Results: Mean patient age was 56.5 yr. We found no difference between the preoperative and the 6-mo postoperative mean IIEF-EF domain score (27.2 vs, 26.7, respectively; p = 0.35). No difference was found in penile colour Doppler evaluation between the preoperative and postoperative periods (all p values ≥0.3). We found no differences in penile length and circumference between the preoperative and postoperative evaluation either in the flaccid or in the erect state. Mean flaccid penile length (cm; preop vs. postop): 13.2 vs. 13 (p = 0.6). Mean flaccid penile circumference (cm; preop vs. postop): 11.1 vs. 11 (p = 0.7). Mean erect penile length (cm; preop vs. postop): 16.8 vs. 16.5 (p = 0.08). Mean erect penile circumference (cm; preop vs. postop): 15.6 vs. 15.3 (p = 0.2). Conclusions: This is the first report on penile changes in flaccidity and at maximum erection after BNSRRP in patients treated by one high-volume surgeon. The postoperative preservation of erectile function positively correlated with the maintenance of penile length following surgery. We found no change in penile size after surgery.

KW - Erectile dysfunction

KW - Penile size

KW - Radical prostatectomy

UR - http://www.scopus.com/inward/record.url?scp=34547166039&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34547166039&partnerID=8YFLogxK

U2 - 10.1016/j.eururo.2007.03.050

DO - 10.1016/j.eururo.2007.03.050

M3 - Article

VL - 52

SP - 702

EP - 707

JO - European Urology

JF - European Urology

SN - 0302-2838

IS - 3

ER -