Presynaptic AMPA receptors: More than just ion channels?

Ursula Schenk; Michela Matteoli

doi:10.1016/j.biolcel.2004.01.008

Presynaptic AMPA receptors: More than just ion channels?

Ursula Schenk, Michela Matteoli

Istituto Clinico Humanitas

Research output: Contribution to journal › Article

Abstract

AMPA receptor ion channels are of paramount importance for postsynaptic excitation. Several reports demonstrate that AMPA receptors are present in the presynaptic compartment and point to a role of these receptors in the modulation of presynaptic function. We discuss here the possibility that not only ion influx through the receptor, but also biochemical cascades, activated by ligand binding and independent from ion flux, might contribute to AMPA mediated presynaptic modulation.

Original language	English
Pages (from-to)	257-260
Number of pages	4
Journal	Biology of the cell / under the auspices of the European Cell Biology Organization
Volume	96
Issue number	4
DOIs	https://doi.org/10.1016/j.biolcel.2004.01.008
Publication status	Published - May 2004

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Keywords

AMPA receptors
Neurotransmitter release
Presynapse
Signal transduction

ASJC Scopus subject areas

Cell Biology

Cite this

Schenk, U., & Matteoli, M. (2004). Presynaptic AMPA receptors: More than just ion channels? Biology of the cell / under the auspices of the European Cell Biology Organization, 96(4), 257-260. https://doi.org/10.1016/j.biolcel.2004.01.008

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Access to Document

10.1016/j.biolcel.2004.01.008