Abstract
AMPA receptor ion channels are of paramount importance for postsynaptic excitation. Several reports demonstrate that AMPA receptors are present in the presynaptic compartment and point to a role of these receptors in the modulation of presynaptic function. We discuss here the possibility that not only ion influx through the receptor, but also biochemical cascades, activated by ligand binding and independent from ion flux, might contribute to AMPA mediated presynaptic modulation.
Original language | English |
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Pages (from-to) | 257-260 |
Number of pages | 4 |
Journal | Biology of the cell / under the auspices of the European Cell Biology Organization |
Volume | 96 |
Issue number | 4 |
DOIs | |
Publication status | Published - May 2004 |
Keywords
- AMPA receptors
- Neurotransmitter release
- Presynapse
- Signal transduction
ASJC Scopus subject areas
- Cell Biology