Prevalence and associations of erectile dysfunction in a sample of Italian males with type 2 diabetes

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Abstract

Aim: The aim of this study was to evaluate the prevalence of erectile dysfunction (ED) in a sample of type 2 diabetic patients. As secondary endpoint, we evaluated the levels of some adipocytokines in patients with and without ED. Material and methods: We enrolled 220 males affected by type 2 diabetes mellitus. We administered the IIEF (International Index of Erectile Function), SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires. We evaluated body mass index, glycemic control, fasting plasma insulin (FPI), homeostasis model assessment of insulin resistance index (HOMA-IR), lipid profile, sexual hormones, adiponectin (ADN), resistin, retinol binding protein-4 (RBP-4), visfatin, vaspin. Results: 52.9% of patients were affected by ED. Patients with a HbA1c 1c was >7% (53mmol/mol). Patients with ED had higher levels of triglycerides, and higher levels of FPI, 9.9μU/ml vs 8.2μU/ml (p

Original languageEnglish
Pages (from-to)329-335
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume108
Issue number2
DOIs
Publication statusPublished - May 1 2015

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Erectile Dysfunction
Type 2 Diabetes Mellitus
Fasting
Nicotinamide Phosphoribosyltransferase
Insulin
Resistin
Retinol-Binding Proteins
Adipokines
Adiponectin
Insulin Resistance
Triglycerides
Body Mass Index
Homeostasis
Anxiety
Hormones
Depression
Lipids

Keywords

  • Erectile dysfunction
  • Hypertriglyceridemia
  • Insulin resistance
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology
  • Medicine(all)

Cite this

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title = "Prevalence and associations of erectile dysfunction in a sample of Italian males with type 2 diabetes",
abstract = "Aim: The aim of this study was to evaluate the prevalence of erectile dysfunction (ED) in a sample of type 2 diabetic patients. As secondary endpoint, we evaluated the levels of some adipocytokines in patients with and without ED. Material and methods: We enrolled 220 males affected by type 2 diabetes mellitus. We administered the IIEF (International Index of Erectile Function), SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires. We evaluated body mass index, glycemic control, fasting plasma insulin (FPI), homeostasis model assessment of insulin resistance index (HOMA-IR), lipid profile, sexual hormones, adiponectin (ADN), resistin, retinol binding protein-4 (RBP-4), visfatin, vaspin. Results: 52.9{\%} of patients were affected by ED. Patients with a HbA1c 1c was >7{\%} (53mmol/mol). Patients with ED had higher levels of triglycerides, and higher levels of FPI, 9.9μU/ml vs 8.2μU/ml (p",
keywords = "Erectile dysfunction, Hypertriglyceridemia, Insulin resistance, Type 2 diabetes mellitus",
author = "Giuseppe Derosa and Davide Romano and Carmine Tinelli and Angela D'Angelo and Pamela Maffioli",
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AU - Derosa, Giuseppe

AU - Romano, Davide

AU - Tinelli, Carmine

AU - D'Angelo, Angela

AU - Maffioli, Pamela

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Aim: The aim of this study was to evaluate the prevalence of erectile dysfunction (ED) in a sample of type 2 diabetic patients. As secondary endpoint, we evaluated the levels of some adipocytokines in patients with and without ED. Material and methods: We enrolled 220 males affected by type 2 diabetes mellitus. We administered the IIEF (International Index of Erectile Function), SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires. We evaluated body mass index, glycemic control, fasting plasma insulin (FPI), homeostasis model assessment of insulin resistance index (HOMA-IR), lipid profile, sexual hormones, adiponectin (ADN), resistin, retinol binding protein-4 (RBP-4), visfatin, vaspin. Results: 52.9% of patients were affected by ED. Patients with a HbA1c 1c was >7% (53mmol/mol). Patients with ED had higher levels of triglycerides, and higher levels of FPI, 9.9μU/ml vs 8.2μU/ml (p

AB - Aim: The aim of this study was to evaluate the prevalence of erectile dysfunction (ED) in a sample of type 2 diabetic patients. As secondary endpoint, we evaluated the levels of some adipocytokines in patients with and without ED. Material and methods: We enrolled 220 males affected by type 2 diabetes mellitus. We administered the IIEF (International Index of Erectile Function), SAS (self-rating anxiety scale) and SDS (self-rating depression scale) questionnaires. We evaluated body mass index, glycemic control, fasting plasma insulin (FPI), homeostasis model assessment of insulin resistance index (HOMA-IR), lipid profile, sexual hormones, adiponectin (ADN), resistin, retinol binding protein-4 (RBP-4), visfatin, vaspin. Results: 52.9% of patients were affected by ED. Patients with a HbA1c 1c was >7% (53mmol/mol). Patients with ED had higher levels of triglycerides, and higher levels of FPI, 9.9μU/ml vs 8.2μU/ml (p

KW - Erectile dysfunction

KW - Hypertriglyceridemia

KW - Insulin resistance

KW - Type 2 diabetes mellitus

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