TY - JOUR
T1 - Prevalence and correlates of new-onset left ventricular geometric abnormalities in a general population
T2 - the PAMELA study
AU - Cuspidi, Cesare
AU - Facchetti, Rita
AU - Bombelli, Michele
AU - Sala, Carla
AU - Tadic, Marijana
AU - Grassi, Guido
AU - Mancia, Giuseppe
PY - 2016/4/28
Y1 - 2016/4/28
N2 - AIM:: We sought to evaluate new-onset abnormal LV (left ventricle) patterns and their correlates over a 10-year period in members of the general population enrolled in the Pressioni Arteriose Monitorate e Loro Associazioni study. METHODS:: The study included 817 patients with normal LV geometry at baseline evaluation having a readable echocardiogram at the end of follow-up. Cut-points for abnormal LV geometric patterns were derived from reference values of the healthy fraction of the Pressioni Arteriose Monitorate e Loro Associazioni population. RESULTS:: Over a 10-year period 39% of participants progressed to abnormal LV geometric patterns as follows: LV concentric remodelling (15.2%), eccentric dilated left ventricular hypertrophy (LVH) (8.4%), concentric LVH (7.9%), eccentric nondilated LVH (6.8%), and concentric dilated LVH (0.7%). Age [odds ratio (OR): 1.039; 95% confidence interval (CI) 1.023–1.056, P?
AB - AIM:: We sought to evaluate new-onset abnormal LV (left ventricle) patterns and their correlates over a 10-year period in members of the general population enrolled in the Pressioni Arteriose Monitorate e Loro Associazioni study. METHODS:: The study included 817 patients with normal LV geometry at baseline evaluation having a readable echocardiogram at the end of follow-up. Cut-points for abnormal LV geometric patterns were derived from reference values of the healthy fraction of the Pressioni Arteriose Monitorate e Loro Associazioni population. RESULTS:: Over a 10-year period 39% of participants progressed to abnormal LV geometric patterns as follows: LV concentric remodelling (15.2%), eccentric dilated left ventricular hypertrophy (LVH) (8.4%), concentric LVH (7.9%), eccentric nondilated LVH (6.8%), and concentric dilated LVH (0.7%). Age [odds ratio (OR): 1.039; 95% confidence interval (CI) 1.023–1.056, P?
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U2 - 10.1097/HJH.0000000000000956
DO - 10.1097/HJH.0000000000000956
M3 - Article
JO - Journal of Hypertension
JF - Journal of Hypertension
SN - 0263-6352
ER -