T1he goal of the study is to characterize the neuropsychiatric symptomatology and its evolution of a large group of cerebrovascular injured patients during the first year post-stroke. The Neuropsychiatric Inventory (NPI, Cummings et al., 1994), was administered to a sample of 63 patients with unilateral cerebrovascular focal lesion, divided into 3 independent groups on the basis of the stroke distance: 23 patients were evaluated at 2 months after stroke; 22 at 6 months and 18 patients were studied at 1 year of distance. Sixty-one healthy subjects were recruited and evaluated for controls. A wide range of neuropsychiatric disorders were significantly founded in the brain-damaged population with respect to the control group: mostly depression (66%), irritability (46%), agitation (35%), apathy (33%) and anxiety (25%). Modifications in terms of higher agitation, depression, anxiety, irritability characterised the whole year after stroke. However, other symptoms were founded depending on the stroke distance: euphoria and aberrant motor behaviours were significantly present only at 2 months; depression, although present yet at 2 months, become more relevant at 6 months and decreased at one year of distance. In the same period (6 months), other disorders typically related to depression such as apathy, night time disturbances, obsessive/compulsive disorders, not significantly present at 2 months, increased and reached the statistical significance. At one year, while depression and agitation decreased with respect to 6 months patients (although higher than controls), apathy and anxiety persisted and irritability and eating disorders increased.
|Translated title of the contribution||Prevalence and evolution of neuropsychiatric disturbances after stroke: Preliminary data|
|Number of pages||7|
|Journal||Rivista di Neurobiologia|
|Publication status||Published - 2001|
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