Prevalence and factors associated with circadian blood pressure patterns in hypertensive patients

Alejandro De La Sierra, Josep Redon, José R. Banegas, Julián Segura, Gianfranco Parati, Manuel Gorostidi, Juan J. De La Cruz, Javier Sobrino, José L. Llisterri, Javier Alonso, Ernest Vinyoles, Vicente Pallarés, Antonio Sarría, Pedro Aranda, Luis M. Ruilope

Research output: Contribution to journalArticlepeer-review


Ambulatory blood pressure (BP) monitoring has become useful in the diagnosis and management of hypertensive individuals. In addition to 24-hour values, the circadian variation of BP adds prognostic significance in predicting cardiovascular outcome. However, the magnitude of circadian BP patterns in large studies has hardly been noticed. Our aims were to determine the prevalence of circadian BP patterns and to assess clinical conditions associated with the nondipping status in groups of both treated and untreated hypertensive subjects, studied separately. Clinical data and 24-hour ambulatory BP monitoring were obtained from 42 947 hypertensive patients included in the Spanish Society of Hypertension Ambulatory Blood Pressure Monitoring Registry. They were 8384 previously untreated and 34 563 treated hypertensives. Twenty-four-hour ambulatory BP monitoring was performed with an oscillometric device (SpaceLabs 90207). A nondipping pattern was defined when nocturnal systolic BP dip was

Original languageEnglish
Pages (from-to)466-472
Number of pages7
Issue number3
Publication statusPublished - Mar 2009


  • Ambulatory blood pressure monitoring
  • Cardiovascular risk factors
  • Circadian blood pressure pattern
  • Hypertension
  • Nocturnal blood pressure dip

ASJC Scopus subject areas

  • Internal Medicine


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