Prevalence and orthopedic management of foot and ankle deformities in Charcot–Marie–Tooth disease

Matilde Laurá, Dishan Singh, Gita Ramdharry, Jasper Morrow, Mariola Skorupinska, Davide Pareyson, Joshua Burns, Richard A. Lewis, Steven S. Scherer, David N. Herrmann, Nicholas Cullen, Christopher Bradish, Luca Gaiani, Nicolò Martinelli, Paul Gibbons, Glenn Pfeffer, Phinit Phisitkul, Keith Wapner, James Sanders, Sam FlemisterMichael E. Shy, Mary M. Reilly, on behalf of the Inherited Neuropathies Consortium

Research output: Contribution to journalArticle

Abstract

Introduction: Foot deformities are frequent complications in Charcot–Marie–Tooth disease (CMT) patients, often requiring orthopedic surgery. However, there are no prospective, randomized studies on surgical management, and there is variation in the approaches among centers both within and between countries. Methods: In this study we assessed the frequency of foot deformities and surgery among patients recruited into the Inherited Neuropathies Consortium (INC). We also designed a survey addressed to orthopedic surgeons at INC centers to determine whether surgical approaches to orthopedic complications in CMT are variable. Results: Foot deformities were reported in 71% of CMT patients; 30% of the patients had surgery. Survey questions were answered by 16 surgeons working in different specialized centers. Most of the respondents were foot and ankle surgeons. There was marked variation in surgical management. Discussion: Our findings confirm that the approaches to orthopedic management of CMT are varied. We identify areas that require further research. Muscle Nerve 57: 255–259, 2018.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalMuscle and Nerve
Volume57
Issue number2
DOIs
Publication statusPublished - Feb 1 2018

    Fingerprint

Keywords

  • Charcot–Marie–Tooth disease
  • foot deformities
  • foot surgery
  • orthopedic complications
  • pes cavus
  • survey

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Cite this

Laurá, M., Singh, D., Ramdharry, G., Morrow, J., Skorupinska, M., Pareyson, D., Burns, J., Lewis, R. A., Scherer, S. S., Herrmann, D. N., Cullen, N., Bradish, C., Gaiani, L., Martinelli, N., Gibbons, P., Pfeffer, G., Phisitkul, P., Wapner, K., Sanders, J., ... on behalf of the Inherited Neuropathies Consortium (2018). Prevalence and orthopedic management of foot and ankle deformities in Charcot–Marie–Tooth disease. Muscle and Nerve, 57(2), 255-259. https://doi.org/10.1002/mus.25724