Abstract
737 Patients with suspected cosmetic- or medicament-related contact dermatitis were patch tested with 6 emulsifier agents: triethanolamine, cetyl stearyl alcohol, sorbitan sesquioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monooleate, and Amerchol L 101. 39 patients (5.3%) gave 1 or more positive patch tests to emulsifiers. A total of 54 positive reactions were found, 23 of which were clinically relevant, triethanolamine being the most frequent sensitizer. Patients with emulsifier sensitivity generally give a high prevalence of positive patch tests to other common ingredients of topical preparations, such as preservatives or active ingredients. Cosmetics and topical medicaments were detected as the source of sensitization in an equal number of patients. Patch tests with patients' own causative preparations were frequently negative. To avoid overlooking emulsifier sensitivity, it is advisable to test these compounds in patients with contact dermatitis that is possibly due to topical preparations, regardless of whether they have other clinically relevant positive reactions or whether patch tests with their own products are negative.
| Original language | English |
|---|---|
| Pages (from-to) | 68-72 |
| Number of pages | 5 |
| Journal | Contact Dermatitis |
| Volume | 23 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 1990 |
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Keywords
- allergic contact dermatitis
- Amerchol L 101
- cetyl stearyl alcohol
- cosmetics
- emulsifiers
- medicaments
- polyoxyethylene sorbitan monooleate
- polyoxyethylene sorbitan monopalmitate
- sorbitan sesquioleate
- triethanolamine
ASJC Scopus subject areas
- Dermatology
- Toxicology
- Immunology
Cite this
Prevalence and sources of sensitization to emulsifiers : A clinical study. / Tosti, A.; Guerra, L.; Morelli, R.; Bardazzi, F.
In: Contact Dermatitis, Vol. 23, No. 2, 1990, p. 68-72.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence and sources of sensitization to emulsifiers
T2 - A clinical study
AU - Tosti, A.
AU - Guerra, L.
AU - Morelli, R.
AU - Bardazzi, F.
PY - 1990
Y1 - 1990
N2 - 737 Patients with suspected cosmetic- or medicament-related contact dermatitis were patch tested with 6 emulsifier agents: triethanolamine, cetyl stearyl alcohol, sorbitan sesquioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monooleate, and Amerchol L 101. 39 patients (5.3%) gave 1 or more positive patch tests to emulsifiers. A total of 54 positive reactions were found, 23 of which were clinically relevant, triethanolamine being the most frequent sensitizer. Patients with emulsifier sensitivity generally give a high prevalence of positive patch tests to other common ingredients of topical preparations, such as preservatives or active ingredients. Cosmetics and topical medicaments were detected as the source of sensitization in an equal number of patients. Patch tests with patients' own causative preparations were frequently negative. To avoid overlooking emulsifier sensitivity, it is advisable to test these compounds in patients with contact dermatitis that is possibly due to topical preparations, regardless of whether they have other clinically relevant positive reactions or whether patch tests with their own products are negative.
AB - 737 Patients with suspected cosmetic- or medicament-related contact dermatitis were patch tested with 6 emulsifier agents: triethanolamine, cetyl stearyl alcohol, sorbitan sesquioleate, polyoxyethylene sorbitan monopalmitate, polyoxyethylene sorbitan monooleate, and Amerchol L 101. 39 patients (5.3%) gave 1 or more positive patch tests to emulsifiers. A total of 54 positive reactions were found, 23 of which were clinically relevant, triethanolamine being the most frequent sensitizer. Patients with emulsifier sensitivity generally give a high prevalence of positive patch tests to other common ingredients of topical preparations, such as preservatives or active ingredients. Cosmetics and topical medicaments were detected as the source of sensitization in an equal number of patients. Patch tests with patients' own causative preparations were frequently negative. To avoid overlooking emulsifier sensitivity, it is advisable to test these compounds in patients with contact dermatitis that is possibly due to topical preparations, regardless of whether they have other clinically relevant positive reactions or whether patch tests with their own products are negative.
KW - allergic contact dermatitis
KW - Amerchol L 101
KW - cetyl stearyl alcohol
KW - cosmetics
KW - emulsifiers
KW - medicaments
KW - polyoxyethylene sorbitan monooleate
KW - polyoxyethylene sorbitan monopalmitate
KW - sorbitan sesquioleate
KW - triethanolamine
UR - http://www.scopus.com/inward/record.url?scp=0025289275&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025289275&partnerID=8YFLogxK
U2 - 10.1111/j.1600-0536.1990.tb03225.x
DO - 10.1111/j.1600-0536.1990.tb03225.x
M3 - Article
C2 - 2145129
AN - SCOPUS:0025289275
VL - 23
SP - 68
EP - 72
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 2
ER -