Prevalence and time course of post-stroke pain: A multicenter prospective hospital-based study

Stefano Paolucci, Marco Iosa, D. Toni, Piero Barbanti, P. Bovi, Anna Maria Cavallini, Elisa Candeloro, Alessia Mancini, Mauro Mancuso, S. Monaco, Alessio Pieroni, Serena Recchia, Maria Sessa, Davide Strambo, Michele Tinazzi, G. Cruccu, A. Truini

Research output: Contribution to journalArticle

Abstract

Objective. Pain prevalence data for patients at various stages after stroke. Design. Repeated cross-sectional, observational epidemiological study. Setting. Hospital-based multicenter study. Subjects. Four hundred forty-three prospectively enrolled stroke survivors. Methods. Allpatientsunderwentbedside clinical examination. The different types of post-stroke pain (central post-stroke pain, musculoskeletal pains, shoulder pain, spasticity-related pain, and headache) were diagnosed with widely accepted criteria during the acute, subacute, and chronic stroke stages. Differences among the three stages were analyzed with v2-tests. Results. The mean overall prevalence of pain was 29.56% (14.06% in the acute, 42.73% in the subacute, and 31.90% in the chronic post-stroke stage). Time course differed significantly according to the various pain types (P< 0.001). The prevalence of musculoskeletal and shoulder pain was higher in the subacute and chronic than in the acute stages after stroke; the prevalence of spasticity-related pain peaked in the chronic stage. Conversely, headache manifested in the acute post-stroke stage. The prevalence of central post-stroke pain was higher in the subacute and chronic than in the acute poststroke stage. Fewer than 25% of the patients with central post-stroke pain received drug treatment. Conclusions. Pain after stroke is more frequent in the subacute and chronic phase than in the acute phase, but it is still largely undertreated.

Original languageEnglish
Pages (from-to)924-930
Number of pages7
JournalPain Medicine (United States)
Volume17
Issue number5
DOIs
Publication statusPublished - May 1 2016

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Stroke
Pain
Musculoskeletal Pain
Shoulder Pain
Headache
Multicenter Studies
Observational Studies
Survivors
Epidemiologic Studies
Pharmaceutical Preparations

Keywords

  • Central post-stroke pain
  • Hemiplegic shoulder pain
  • Spasticity
  • Stroke

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine

Cite this

Prevalence and time course of post-stroke pain : A multicenter prospective hospital-based study. / Paolucci, Stefano; Iosa, Marco; Toni, D.; Barbanti, Piero; Bovi, P.; Cavallini, Anna Maria; Candeloro, Elisa; Mancini, Alessia; Mancuso, Mauro; Monaco, S.; Pieroni, Alessio; Recchia, Serena; Sessa, Maria; Strambo, Davide; Tinazzi, Michele; Cruccu, G.; Truini, A.

In: Pain Medicine (United States), Vol. 17, No. 5, 01.05.2016, p. 924-930.

Research output: Contribution to journalArticle

Paolucci, S, Iosa, M, Toni, D, Barbanti, P, Bovi, P, Cavallini, AM, Candeloro, E, Mancini, A, Mancuso, M, Monaco, S, Pieroni, A, Recchia, S, Sessa, M, Strambo, D, Tinazzi, M, Cruccu, G & Truini, A 2016, 'Prevalence and time course of post-stroke pain: A multicenter prospective hospital-based study', Pain Medicine (United States), vol. 17, no. 5, pp. 924-930. https://doi.org/10.1093/pm/pnv019
Paolucci, Stefano ; Iosa, Marco ; Toni, D. ; Barbanti, Piero ; Bovi, P. ; Cavallini, Anna Maria ; Candeloro, Elisa ; Mancini, Alessia ; Mancuso, Mauro ; Monaco, S. ; Pieroni, Alessio ; Recchia, Serena ; Sessa, Maria ; Strambo, Davide ; Tinazzi, Michele ; Cruccu, G. ; Truini, A. / Prevalence and time course of post-stroke pain : A multicenter prospective hospital-based study. In: Pain Medicine (United States). 2016 ; Vol. 17, No. 5. pp. 924-930.
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AU - Bovi, P.

AU - Cavallini, Anna Maria

AU - Candeloro, Elisa

AU - Mancini, Alessia

AU - Mancuso, Mauro

AU - Monaco, S.

AU - Pieroni, Alessio

AU - Recchia, Serena

AU - Sessa, Maria

AU - Strambo, Davide

AU - Tinazzi, Michele

AU - Cruccu, G.

AU - Truini, A.

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