Prevalence, incidence, and clinical impact of sarcopenia: facts, numbers, and epidemiology—update 2014

John E. Morley, Stefan D. Anker, Stephan von Haehling

Research output: Contribution to journalArticle

Abstract

Sarcopenia is now defined as a decline in walking speed or grip strength associated with low muscle mass. Sarcopenia leads to loss of mobility and function, falls, and mortality. Sarcopenia is a major cause of frailty, but either condition can occur without the other being present. Sarcopenia is present in about 5 to 10 % of persons over 65 years of age. It has multiple causes including disease, decreased caloric intake, poor blood flow to muscle, mitochondrial dysfunction, a decline in anabolic hormones, and an increase in proinflammatory cytokines. Basic therapy includes resistance exercise and protein and vitamin D supplementation. There is now a simple screening test available for sarcopenia—SARC-F. All persons 60 years and older should be screened for sarcopenia and treated when appropriate.

Original languageEnglish
Pages (from-to)253-259
Number of pages7
JournalJournal of Cachexia, Sarcopenia and Muscle
Volume5
Issue number4
DOIs
Publication statusPublished - Nov 26 2014

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physiology (medical)

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