Prevalence of and risk factors for fungal vaginitis caused by non-albicans species

Arsenio Spinillo, Ezio Capuzzo, Roberte Gulminetti, Piero Marone, Laura Colonna, Gaia Piazzi

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: Our purpose was to evaluate the prevalence of symptomatic yeast vaginitis caused by nona/to/cans species among patients attending a vaginitis clinic over an 8-year period. STUDY DESIGN: A retrospective study of 1263 patients with symptomatic yeast vaginitis confirmed by culture techniques was performed. RESULTS: The prevalence of symptomatic fungal vaginitis caused by non-alb/cans species increased from 9.9% (10/101) in 1988 to 17.2% (36/209) in 1995 (x2 for trend = 9.33, p = 0.002). Non-albicans species were found more frequently in known human immunodeficiency virus-seropositive patients (23/102 vs 143/1161, odds ratio 2.07, 95% confidence interval 1.2 to 3.46) than in seronegative subjects or subjects of unknown status for the virus. Recurrent vaginal candidiasis was an additional risk factor for vaginitis caused by non-albicans species (odds ratio 2.47, 95% confidence interval 1.72 to 3.52). The increase in non-albicans isolates during the study period was confirmed in stratified analysis and in the subgroup of self-referred patients with no history of either human immunodeficiency virus infection or recurrent vaginal candidiasis. CONCLUSION: The prevalence of fungal vaginitis caused by non-albicans species has increased sharply in the setting of a vaginitis clinic. The characteristics of risk factors suggest that fungal cultures should be done routinely in human immunodeficiencv virus-serooositive subjects with susoected vaainal candidiasis and in patients with recurrent vaginal infection.

Original languageEnglish
Pages (from-to)138-141
Number of pages4
JournalAmerican Journal of Obstetrics and Gynecology
Volume176
Issue number1 I
Publication statusPublished - 1997

Keywords

  • Fungal infections
  • Mycotic vaginitis
  • Non-albicans species

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynaecology

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