Prevalence of anticardiolipin antibodies in juvenile chronic arthritis

The prevalence of anticardiolipin antibodies was evaluated in 70 children with juvenile chronic arthritis (CA), in 25 adult patients with rheumatoid arthritis, in 42 healthy chiklren and in 40 adult controls. Thirty seven (53%) patients with JCA were positive for IgG or IgM anticardiolipin antibodies, or both, and 30 (43%/) for IgG anticardiolipin antibodies. In contrast, only seven (28%/9) adult patients with iheumatoid arthritis presented anticardiolipin antibodies, which were of IgG class in four (16%) cases. IgG anticardiolipin antibodies were negative in all control subjects while IgM anticardiolipin antibodies were detected in two (5%/6) chilren and in four (10%) adult controls. No correlations were found in patients with JCA between the presence or titres of anticardiolipin antibodies and various cfinical or laboratory variables. No patient with anticardiolipin antibodies showed any feature of the anticardiolipin syndrome.