One hundred and two consecutive symptomatic patients (57 males and 45 females) affected by gastroesophageal reflux disease underwent endoscopy with multiple mucosal biopsies of the lower esophageal portion. Twelve patients (11.8 %) showed histologically proven columnar metaplasia. Esophagitis and hiatal hernia associated with esophagitis were the most frequent clinical conditions in patients with Barrett's esophagus (B.E.). Endoscopic examination showed atypical course of the squamocolumnar junction in 6 patients; in the remaining cases serious inflammatory disease did not allow to correctly recognize the squamocolumnar junction. No specimens of B.E. showed epithelial dysplasia. Barrett's esophagus may occur in symptomatic patients with benign diseases of the lower esophagus. Long term prospective follow-up studies are needed in order to understand the real risk of developing adenocarcinoma in patients affected by B.E.
|Translated title of the contribution||Prevalence of Barrett's esophagus in patients with gastroesophageal reflux disease|
|Number of pages||8|
|Publication status||Published - Sep 1988|
- Barrett's esophagus
- gastro-esophageal reflux
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging