Prevalence of hepatitis C virus antibodies in Italian blood donors

G. Sirchia; D. Almini; A. Bellobuono; A. M. Giovanetti; M. Marconi; F. Mercuriali; F. Mozzi; A. Parravicini; M. Pizzi; F. Zanuso; Cooperative Group Italian Cooperative Group

Prevalence of hepatitis C virus antibodies in Italian blood donors

G. Sirchia, D. Almini, A. Bellobuono, A. M. Giovanetti, M. Marconi, F. Mercuriali, F. Mozzi, A. Parravicini, M. Pizzi, F. Zanuso, Cooperative Group Italian Cooperative Group

Research output: Contribution to journal › Article › peer-review

Abstract

11,117 blood donors from 24 blood transfusion services evenly distributed throughout the various Italian regions were tested for the presence of hepatitis C virus (HCV) antibodies in the serum and serum alanine aminotransferase (ALT) level. The results are as follows: (1) anti-HCV seroprevalence in Italy was 0.87% with a difference between Northern and Southern regions (0.68 vs. 1.37%) and between younger and older subjects (0.62 vs. 1.21%); (2) prevalence of elevated ALT levels was 4.74% without a North-South effect (except than for markedly elevated ALT levels); (3) anti-HCV seroprevalence was higher in subjects with elevated ALT (5.0%), with a North-South effect (2.2 vs. 9.9%) and particularly high (19.2%) in subjects with markedly elevated ALT; (4) ALT levels were elevated in 26.2% of anti-HCV positive subjects, with a North-South effect (14 vs. 40.5%).

Original language	English
Pages (from-to)	26-29
Number of pages	4
Journal	Vox Sanguinis
Volume	59
Issue number	1
Publication status	Published - 1990

ASJC Scopus subject areas

Hematology

Cite this

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title = "Prevalence of hepatitis C virus antibodies in Italian blood donors",

abstract = "11,117 blood donors from 24 blood transfusion services evenly distributed throughout the various Italian regions were tested for the presence of hepatitis C virus (HCV) antibodies in the serum and serum alanine aminotransferase (ALT) level. The results are as follows: (1) anti-HCV seroprevalence in Italy was 0.87% with a difference between Northern and Southern regions (0.68 vs. 1.37%) and between younger and older subjects (0.62 vs. 1.21%); (2) prevalence of elevated ALT levels was 4.74% without a North-South effect (except than for markedly elevated ALT levels); (3) anti-HCV seroprevalence was higher in subjects with elevated ALT (5.0%), with a North-South effect (2.2 vs. 9.9%) and particularly high (19.2%) in subjects with markedly elevated ALT; (4) ALT levels were elevated in 26.2% of anti-HCV positive subjects, with a North-South effect (14 vs. 40.5%).",

author = "G. Sirchia and D. Almini and A. Bellobuono and Giovanetti, {A. M.} and M. Marconi and F. Mercuriali and F. Mozzi and A. Parravicini and M. Pizzi and F. Zanuso and {Italian Cooperative Group}, {Cooperative Group}",

year = "1990",

language = "English",

volume = "59",

pages = "26--29",

journal = "Vox Sanguinis",

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TY - JOUR

T1 - Prevalence of hepatitis C virus antibodies in Italian blood donors

AU - Sirchia, G.

AU - Almini, D.

AU - Bellobuono, A.

AU - Giovanetti, A. M.

AU - Marconi, M.

AU - Mercuriali, F.

AU - Mozzi, F.

AU - Parravicini, A.

AU - Pizzi, M.

AU - Zanuso, F.

AU - Italian Cooperative Group, Cooperative Group

PY - 1990

Y1 - 1990

N2 - 11,117 blood donors from 24 blood transfusion services evenly distributed throughout the various Italian regions were tested for the presence of hepatitis C virus (HCV) antibodies in the serum and serum alanine aminotransferase (ALT) level. The results are as follows: (1) anti-HCV seroprevalence in Italy was 0.87% with a difference between Northern and Southern regions (0.68 vs. 1.37%) and between younger and older subjects (0.62 vs. 1.21%); (2) prevalence of elevated ALT levels was 4.74% without a North-South effect (except than for markedly elevated ALT levels); (3) anti-HCV seroprevalence was higher in subjects with elevated ALT (5.0%), with a North-South effect (2.2 vs. 9.9%) and particularly high (19.2%) in subjects with markedly elevated ALT; (4) ALT levels were elevated in 26.2% of anti-HCV positive subjects, with a North-South effect (14 vs. 40.5%).

AB - 11,117 blood donors from 24 blood transfusion services evenly distributed throughout the various Italian regions were tested for the presence of hepatitis C virus (HCV) antibodies in the serum and serum alanine aminotransferase (ALT) level. The results are as follows: (1) anti-HCV seroprevalence in Italy was 0.87% with a difference between Northern and Southern regions (0.68 vs. 1.37%) and between younger and older subjects (0.62 vs. 1.21%); (2) prevalence of elevated ALT levels was 4.74% without a North-South effect (except than for markedly elevated ALT levels); (3) anti-HCV seroprevalence was higher in subjects with elevated ALT (5.0%), with a North-South effect (2.2 vs. 9.9%) and particularly high (19.2%) in subjects with markedly elevated ALT; (4) ALT levels were elevated in 26.2% of anti-HCV positive subjects, with a North-South effect (14 vs. 40.5%).

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C2 - 2118697

AN - SCOPUS:0025277562

VL - 59

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JO - Vox Sanguinis

JF - Vox Sanguinis

SN - 0042-9007

IS - 1

ER -

Prevalence of hepatitis C virus antibodies in Italian blood donors

Abstract

ASJC Scopus subject areas

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