Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy

Alessandro Filla, Giuseppe De Michele, Roberto Marconi, Luigi Bucci, Carmine Carillo, Anna Elisa Castellano, Lucio Iorio, Claudio Kniahynicki, Francesco Rossi, Giuseppe Campanella

Research output: Contribution to journalArticle

Abstract

An epidemiological survey of hereditary ataxias and paraplegias was conducted in Molise, a region of Italy (335, 211 inhabitants on 1 January 1989). Total prevalence was 7.5 x 10-5 inhabitants (95% confidence limits 4.8-11.1). There were 7 patients with Friedreich's disease, 5 with early onset cerebellar ataxia with retained tendon reflexes, 4 with ataxia-telangiectasia, 9 with hereditary spastic paraplegias (2 autosomal dominant and 7 autosomal recessive cases). There was no patient with autosomal dominant cerebellar ataxia.

Original languageEnglish
Pages (from-to)351-353
Number of pages3
JournalJournal of Neurology
Volume239
Issue number6
DOIs
Publication statusPublished - Jun 1992

Keywords

  • Epidemiology
  • Hereditary ataxias
  • Hereditary spastic paraplegias

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    Filla, A., De Michele, G., Marconi, R., Bucci, L., Carillo, C., Castellano, A. E., Iorio, L., Kniahynicki, C., Rossi, F., & Campanella, G. (1992). Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy. Journal of Neurology, 239(6), 351-353. https://doi.org/10.1007/BF00867594