Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy

Alessandro Filla, Giuseppe De Michele, Roberto Marconi, Luigi Bucci, Carmine Carillo, Anna Elisa Castellano, Lucio Iorio, Claudio Kniahynicki, Francesco Rossi, Giuseppe Campanella

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

An epidemiological survey of hereditary ataxias and paraplegias was conducted in Molise, a region of Italy (335, 211 inhabitants on 1 January 1989). Total prevalence was 7.5 x 10-5 inhabitants (95% confidence limits 4.8-11.1). There were 7 patients with Friedreich's disease, 5 with early onset cerebellar ataxia with retained tendon reflexes, 4 with ataxia-telangiectasia, 9 with hereditary spastic paraplegias (2 autosomal dominant and 7 autosomal recessive cases). There was no patient with autosomal dominant cerebellar ataxia.

Original languageEnglish
Pages (from-to)351-353
Number of pages3
JournalJournal of Neurology
Volume239
Issue number6
DOIs
Publication statusPublished - Jun 1992

Fingerprint

Hereditary Spastic Paraplegia
Spinocerebellar Degenerations
Italy
Friedreich Ataxia
Ataxia Telangiectasia
Cerebellar Ataxia
Paraplegia

Keywords

  • Epidemiology
  • Hereditary ataxias
  • Hereditary spastic paraplegias

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Filla, A., De Michele, G., Marconi, R., Bucci, L., Carillo, C., Castellano, A. E., ... Campanella, G. (1992). Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy. Journal of Neurology, 239(6), 351-353. https://doi.org/10.1007/BF00867594

Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy. / Filla, Alessandro; De Michele, Giuseppe; Marconi, Roberto; Bucci, Luigi; Carillo, Carmine; Castellano, Anna Elisa; Iorio, Lucio; Kniahynicki, Claudio; Rossi, Francesco; Campanella, Giuseppe.

In: Journal of Neurology, Vol. 239, No. 6, 06.1992, p. 351-353.

Research output: Contribution to journalArticle

Filla, A, De Michele, G, Marconi, R, Bucci, L, Carillo, C, Castellano, AE, Iorio, L, Kniahynicki, C, Rossi, F & Campanella, G 1992, 'Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy', Journal of Neurology, vol. 239, no. 6, pp. 351-353. https://doi.org/10.1007/BF00867594
Filla, Alessandro ; De Michele, Giuseppe ; Marconi, Roberto ; Bucci, Luigi ; Carillo, Carmine ; Castellano, Anna Elisa ; Iorio, Lucio ; Kniahynicki, Claudio ; Rossi, Francesco ; Campanella, Giuseppe. / Prevalence of hereditary ataxias and spastic paraplegias in Molise, a region of Italy. In: Journal of Neurology. 1992 ; Vol. 239, No. 6. pp. 351-353.
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