Prevalence of human papillomavirus infection in Italian and immigrant women

P. Paba, G. Morosetti, A. A. Criscuolo, V. Chiusuri, F. Marcuccilli, F. Sesti, E. Piccione, C. F. Perno, Marco Ciotti

Research output: Contribution to journalArticlepeer-review


Human papillomavirus (HPV) is the most common sexually transmitted agent worldwide. Prevalence varies according to the geographic regions, and is highest in developing countries. Geographic differences exist also in the detection rate of oncogenic types in malignant cervical lesions. In this study, the prevalence of HPV infection as well as the spectrum of HPV types was evaluated in Italian and immigrant women of the urban area of Rome. Several risk factors (age at first intercourse, number of partners, smoking, pregnancy, age at first pregnancy, contraception, education, and menarche) were taken into consideration. Overall, there was a high prevalence of HPV infection in the two groups studied. No significant differences were observed in the spectrum of HPV types detected. HPV 16 and 18 were the types detected more frequently in both groups. Interestingly, HPV 54 and 70 were found only in the immigrants. Whether this finding reflects a recent introduction of these HPV types in the population studied remains to be established. Monitoring of HPV types in the population is advisable, especially in countries like Italy which is a destination and a gateway for immigrants directed towards north and central Europe. The introduction of high risk HPV variants may have a clinical impact and affect the diagnostic procedures.

Original languageEnglish
Pages (from-to)1055-1062
Number of pages8
JournalInternational Journal of Immunopathology and Pharmacology
Issue number4
Publication statusPublished - Oct 2012


  • HPV
  • HPV genotype
  • HPV prevalence
  • Immigrants

ASJC Scopus subject areas

  • Pharmacology
  • Immunology
  • Immunology and Allergy


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