Prevalence of neurological involvement and malformative/systemic syndromes in a- and V-pattern strabismus

Anna Dickmann, Rosa Parrilla, Stefania Aliberti, Vittoria Perrotta, Annabella Salerni, Gustavo Savino, Sergio Petroni

Research output: Contribution to journalArticle

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Abstract

Purpose: To evaluate the prevalence of neurological involvement and malformative/systemic syndromes in A- and V-patterns with respect to other kinds of infantile concomitant strabismus. Methods: A retrospective comparative study of 14,006 consecutive patients examined in the Pediatric Ophthalmology and Strabismus Unit at the Catholic University of Rome between January 2002 and February 2010 was carried out. A total of 2.72% (385) of patients presented with concomitant constant infantile strabismus associated with A- and V- patterns (study group; mean age 8 years; range: 8 months 37 years; male 211, female 174). Another 377 consecutive patients affected by infantile concomitant strabismus without A- or V- patterns were used as controls (control group; mean age 9 years, range: 134 years; male 194, female 183). All patients underwent a complete ophthalmologic and orthoptic examination with ocular motility evaluation and prism cover test or the Hirschberg test in primary, up and down gaze positions, as well as cycloplegic retinoscopy. The angle of deviation was evaluated at near (33 cm) and distance fixation (6 m) with full correction of refraction. Results: Neurological involvement and malformative/systemic syndromes were observed in 30.4% of the study group and in 19.8% of patients in the control group (P <0.001). Patients with A-pattern showed a greater prevalence of neurological impairment, hydrocephalus and meningomyelocele, while those affected by V-pattern exhibited a greater prevalence of craniosynostosis and malformative syndromes. Conclusions: Neurological involvement and malformative/systemic syndromes seem to be more evident in patients presenting with A- and V-pattern strabismus.

Original languageEnglish
Pages (from-to)302-305
Number of pages4
JournalOphthalmic Epidemiology
Volume19
Issue number5
DOIs
Publication statusPublished - Oct 2012

Fingerprint

Strabismus
Retinoscopy
Orthoptics
Mydriatics
Meningomyelocele
Craniosynostoses
Control Groups
Ophthalmology
Hydrocephalus
Retrospective Studies
Pediatrics

Keywords

  • AV-patterns
  • Epidemiology
  • Malformative syndromes
  • Neurological disorders
  • Strabismus

ASJC Scopus subject areas

  • Ophthalmology
  • Epidemiology

Cite this

Prevalence of neurological involvement and malformative/systemic syndromes in a- and V-pattern strabismus. / Dickmann, Anna; Parrilla, Rosa; Aliberti, Stefania; Perrotta, Vittoria; Salerni, Annabella; Savino, Gustavo; Petroni, Sergio.

In: Ophthalmic Epidemiology, Vol. 19, No. 5, 10.2012, p. 302-305.

Research output: Contribution to journalArticle

Dickmann, Anna ; Parrilla, Rosa ; Aliberti, Stefania ; Perrotta, Vittoria ; Salerni, Annabella ; Savino, Gustavo ; Petroni, Sergio. / Prevalence of neurological involvement and malformative/systemic syndromes in a- and V-pattern strabismus. In: Ophthalmic Epidemiology. 2012 ; Vol. 19, No. 5. pp. 302-305.
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AU - Aliberti, Stefania

AU - Perrotta, Vittoria

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AU - Savino, Gustavo

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AB - Purpose: To evaluate the prevalence of neurological involvement and malformative/systemic syndromes in A- and V-patterns with respect to other kinds of infantile concomitant strabismus. Methods: A retrospective comparative study of 14,006 consecutive patients examined in the Pediatric Ophthalmology and Strabismus Unit at the Catholic University of Rome between January 2002 and February 2010 was carried out. A total of 2.72% (385) of patients presented with concomitant constant infantile strabismus associated with A- and V- patterns (study group; mean age 8 years; range: 8 months 37 years; male 211, female 174). Another 377 consecutive patients affected by infantile concomitant strabismus without A- or V- patterns were used as controls (control group; mean age 9 years, range: 134 years; male 194, female 183). All patients underwent a complete ophthalmologic and orthoptic examination with ocular motility evaluation and prism cover test or the Hirschberg test in primary, up and down gaze positions, as well as cycloplegic retinoscopy. The angle of deviation was evaluated at near (33 cm) and distance fixation (6 m) with full correction of refraction. Results: Neurological involvement and malformative/systemic syndromes were observed in 30.4% of the study group and in 19.8% of patients in the control group (P <0.001). Patients with A-pattern showed a greater prevalence of neurological impairment, hydrocephalus and meningomyelocele, while those affected by V-pattern exhibited a greater prevalence of craniosynostosis and malformative syndromes. Conclusions: Neurological involvement and malformative/systemic syndromes seem to be more evident in patients presenting with A- and V-pattern strabismus.

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KW - Epidemiology

KW - Malformative syndromes

KW - Neurological disorders

KW - Strabismus

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