Prevalence of oedema of the lower limbs in multiple sclerosis patients: A vascular and lymphoscintigraphic study

Claudio Solaro, M. Messmer Uccelli, G. Brichetto, G. Augello, G. Taddei, F. Boccardo, F. Buffoni, C. Campisi, L. Lopes, M. A. Battaglia, G. L. Mancardi

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of the study was to evaluate the frequency of oedema of the lower limbs in multiple sclerosis (MS) patients utilizing a multidisciplinary approach. A total of 205 patients with definite MS were included in the study. Seventy-five were male and 130 female, with a mean age of 50.53, mean Expanded Disability Status Scale (EDSS) score of 5.27 and mean disease duration of 16.6 years. Seventy-one patients had a relapsing-remitting (RR) disease course, 85 were secondary progressive (SP) and 49 were primary progressive (PP). Ninety-three patients (45%) showed oedema at the examination. EDSS, disease duration and disease course, but not gender, were statistically different between oedema and non-oedema patients. Out of 93 patients with oedema, 69 agreed to undergo a vascular examination. Of 69 patients, 45 (65.2%) had a CEAP score (specific rating scale for oedema) of 3 (presence of oedema) and 24 (34.8%) had a score of 4 (presence of a trophic disorder). Out of 69 subjects, 33 agreed to undergo a lymphoscintigraphy, which was normal in only 29 extremities out of 66. Lower limb oedema is common in MS patients, especially in those with reduced mobility. Early screening is advised in patients with an elevated EDSS.

Original languageEnglish
Pages (from-to)659-661
Number of pages3
JournalMultiple Sclerosis Journal
Volume12
Issue number5
DOIs
Publication statusPublished - 2006

Keywords

  • Lymphoscintigraphy
  • Multiple sclerosis
  • Oedema

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Prevalence of oedema of the lower limbs in multiple sclerosis patients: A vascular and lymphoscintigraphic study'. Together they form a unique fingerprint.

Cite this