Background and aim of the work. We assessed the prevalence of oral allergy syndrome (OAS) to vegetable foods in subjects suffering from pollinosis, the clusters of association between vegetable foods and pollens, and some clinical parameters likely to play a pathogenetic role. Methods. We admitted to the study 335 patients with pollinosis, in whom we investigated the clinical features of pollinosis and OAS, their respective ages of onset, and the wheal diameters to pollen extracts in subjects with and without OAS. Results. The prevalence of OAS was 23.5%. In patients with OAS wheals were significantly greater to birch and mugwort pollen extracts than in patients without OAS (respectively p = 0.031 and p = 0.040, Mann Whitney U test). The age of onset of pollinosis was significantly lower (p = 0.041) in patients with OAS. A number of clusters of association was found, the most interesting being that between parietaria pollinosis and OAS to zucchini, suggesting the existence of cross-reacting allergens, so far undetected in these two allergenic sources. Conclusions. These findings indicate that OAS, considering the high prevalence of pollinosis in general population, is likely to represent the most common form of food allergy in adults. The lower age of onset of pollinosis and the higher levels of specific IgE (indicated by greater wheals) in subjects with OAS than in those without OAS suggest that sensitization to vegetable foods may result from sensitization to pollen allergens cross-reactive with foods.
|Translated title of the contribution||Prevalence of Oral Allergy Syndrome (OAS) in patients with pollinosis and quantitative analysis of skin reactivity to pollens in subjects with and without OAS|
|Number of pages||4|
|Publication status||Published - 1996|
ASJC Scopus subject areas
- Internal Medicine