Abstract
The prevalence of cutis verticis gyrata was studied in a psychiatric institutional population of 494 patients, the majority of whom were mentally retarded or had chronic schizophrenia. Twenty-two subjects (21 males and 1 female) were found to have primary cutis verticis gyrata, yielding a prevalence of about 4.5%. The frequency of the scalp disorder was 11.4% among mentally retarded patients and 1.7% in schizophrenic subjects. A cytogenetic study was performed on patients with primary cutis verticis gyrata. In 9 out of 21 subjects there was evidence of chromosomal fragile sites: 5 patients had fragile sites on the X-chromosome, in 2 there was fragility of chromosome 12 and in 2, fragility of chromosome 9. The fragile X-site is the genetic marker of the 'fragile X-syndrome', a sex-linked inherited disorder often associated with mental retardation and other neuropathological findings.
| Original language | English |
|---|---|
| Pages (from-to) | 483-486 |
| Number of pages | 4 |
| Journal | Acta Dermato-Venereologica |
| Volume | 70 |
| Issue number | 6 |
| Publication status | Published - 1990 |
Fingerprint
Keywords
- fragile X-syndrome
- mental retardation
- schizophrenia
ASJC Scopus subject areas
- Dermatology
Cite this
Prevalence of primary cutis verticis gyrata in a psychiatric population : Association with chromosomal fragile sites. / Schepis, C.; Palazzo, R.; Cannavo, S. P.; Ragusa, R. M.; Barletta, C.; Spina, E.
In: Acta Dermato-Venereologica, Vol. 70, No. 6, 1990, p. 483-486.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of primary cutis verticis gyrata in a psychiatric population
T2 - Association with chromosomal fragile sites
AU - Schepis, C.
AU - Palazzo, R.
AU - Cannavo, S. P.
AU - Ragusa, R. M.
AU - Barletta, C.
AU - Spina, E.
PY - 1990
Y1 - 1990
N2 - The prevalence of cutis verticis gyrata was studied in a psychiatric institutional population of 494 patients, the majority of whom were mentally retarded or had chronic schizophrenia. Twenty-two subjects (21 males and 1 female) were found to have primary cutis verticis gyrata, yielding a prevalence of about 4.5%. The frequency of the scalp disorder was 11.4% among mentally retarded patients and 1.7% in schizophrenic subjects. A cytogenetic study was performed on patients with primary cutis verticis gyrata. In 9 out of 21 subjects there was evidence of chromosomal fragile sites: 5 patients had fragile sites on the X-chromosome, in 2 there was fragility of chromosome 12 and in 2, fragility of chromosome 9. The fragile X-site is the genetic marker of the 'fragile X-syndrome', a sex-linked inherited disorder often associated with mental retardation and other neuropathological findings.
AB - The prevalence of cutis verticis gyrata was studied in a psychiatric institutional population of 494 patients, the majority of whom were mentally retarded or had chronic schizophrenia. Twenty-two subjects (21 males and 1 female) were found to have primary cutis verticis gyrata, yielding a prevalence of about 4.5%. The frequency of the scalp disorder was 11.4% among mentally retarded patients and 1.7% in schizophrenic subjects. A cytogenetic study was performed on patients with primary cutis verticis gyrata. In 9 out of 21 subjects there was evidence of chromosomal fragile sites: 5 patients had fragile sites on the X-chromosome, in 2 there was fragility of chromosome 12 and in 2, fragility of chromosome 9. The fragile X-site is the genetic marker of the 'fragile X-syndrome', a sex-linked inherited disorder often associated with mental retardation and other neuropathological findings.
KW - fragile X-syndrome
KW - mental retardation
KW - schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=0025005987&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025005987&partnerID=8YFLogxK
M3 - Article
C2 - 1981419
AN - SCOPUS:0025005987
VL - 70
SP - 483
EP - 486
JO - Acta Borealia
JF - Acta Borealia
SN - 0001-5555
IS - 6
ER -