Abstract
Objective: Assessment of the prevalence of the metabolic syndrome (MetS) and its components in Italian obese individuals. Methods: Cross-sectional estimate of MetS prevalence using the IDF definition in 635 obese (BMI ≥ 35 kg/m 2) individuals (286 men, 349 women) aged 19-78 years hospitalised for mass excess treatment. Results: MetS prevalence was significantly (p <0.001) higher in males (75.9%) than in females (61.9%), due to the increased prevalence of 4/5 involved abnormalities. A multivariate binary logistic regression analysis disclosed a contributory independent effect of ageing (p <0.01-0.001), but not of BMI, whereas large waist circumference (p <0.01) and high waist-to-hip ratio (p <0.01) contributed to MetS prevalence only in women. Affected individuals were significantly older (males p = 0.022; females p <0.001), affected men being younger than affected women (p <0.01). The prevailing clinical picture included all abnormalities (21.2% in men, 22.2% in women); in minimal trait MetS (3/5 abnormalities), the prevailing combination was, beside central obesity, hypertension-hyperglycaemia in men (12.4%), and hypertension-dyslipidemia in women (19.4%). Conclusions: MetS is a highly prevalent condition among Italian obese individuals. Prevalence and combinations of involved abnormalities differ considerably between genders and suggest a different pathophysiology of the MetS in men and women, with possible relevance for prevention and treatment of the condition.
| Original language | English |
|---|---|
| Pages (from-to) | 127-137 |
| Number of pages | 11 |
| Journal | Obesity Facts |
| Volume | 5 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Mar 2012 |
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Keywords
- Blood pressure
- Fasting plasma glucose
- HDL cholesterol
- Obesity
- Triglycerides
ASJC Scopus subject areas
- Physiology (medical)
- Health(social science)
Cite this
Prevalence of the metabolic syndrome and its components among obese men and women in Italy. / Lafortuna, Claudio L.; Agosti, Fiorenza; De Col, Alessandra; Pera, Franca; Adorni, Fulvio; Sartorio, Alessandro.
In: Obesity Facts, Vol. 5, No. 1, 03.2012, p. 127-137.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Prevalence of the metabolic syndrome and its components among obese men and women in Italy
AU - Lafortuna, Claudio L.
AU - Agosti, Fiorenza
AU - De Col, Alessandra
AU - Pera, Franca
AU - Adorni, Fulvio
AU - Sartorio, Alessandro
PY - 2012/3
Y1 - 2012/3
N2 - Objective: Assessment of the prevalence of the metabolic syndrome (MetS) and its components in Italian obese individuals. Methods: Cross-sectional estimate of MetS prevalence using the IDF definition in 635 obese (BMI ≥ 35 kg/m 2) individuals (286 men, 349 women) aged 19-78 years hospitalised for mass excess treatment. Results: MetS prevalence was significantly (p <0.001) higher in males (75.9%) than in females (61.9%), due to the increased prevalence of 4/5 involved abnormalities. A multivariate binary logistic regression analysis disclosed a contributory independent effect of ageing (p <0.01-0.001), but not of BMI, whereas large waist circumference (p <0.01) and high waist-to-hip ratio (p <0.01) contributed to MetS prevalence only in women. Affected individuals were significantly older (males p = 0.022; females p <0.001), affected men being younger than affected women (p <0.01). The prevailing clinical picture included all abnormalities (21.2% in men, 22.2% in women); in minimal trait MetS (3/5 abnormalities), the prevailing combination was, beside central obesity, hypertension-hyperglycaemia in men (12.4%), and hypertension-dyslipidemia in women (19.4%). Conclusions: MetS is a highly prevalent condition among Italian obese individuals. Prevalence and combinations of involved abnormalities differ considerably between genders and suggest a different pathophysiology of the MetS in men and women, with possible relevance for prevention and treatment of the condition.
AB - Objective: Assessment of the prevalence of the metabolic syndrome (MetS) and its components in Italian obese individuals. Methods: Cross-sectional estimate of MetS prevalence using the IDF definition in 635 obese (BMI ≥ 35 kg/m 2) individuals (286 men, 349 women) aged 19-78 years hospitalised for mass excess treatment. Results: MetS prevalence was significantly (p <0.001) higher in males (75.9%) than in females (61.9%), due to the increased prevalence of 4/5 involved abnormalities. A multivariate binary logistic regression analysis disclosed a contributory independent effect of ageing (p <0.01-0.001), but not of BMI, whereas large waist circumference (p <0.01) and high waist-to-hip ratio (p <0.01) contributed to MetS prevalence only in women. Affected individuals were significantly older (males p = 0.022; females p <0.001), affected men being younger than affected women (p <0.01). The prevailing clinical picture included all abnormalities (21.2% in men, 22.2% in women); in minimal trait MetS (3/5 abnormalities), the prevailing combination was, beside central obesity, hypertension-hyperglycaemia in men (12.4%), and hypertension-dyslipidemia in women (19.4%). Conclusions: MetS is a highly prevalent condition among Italian obese individuals. Prevalence and combinations of involved abnormalities differ considerably between genders and suggest a different pathophysiology of the MetS in men and women, with possible relevance for prevention and treatment of the condition.
KW - Blood pressure
KW - Fasting plasma glucose
KW - HDL cholesterol
KW - Obesity
KW - Triglycerides
UR - http://www.scopus.com/inward/record.url?scp=84858850494&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858850494&partnerID=8YFLogxK
U2 - 10.1159/000336700
DO - 10.1159/000336700
M3 - Article
C2 - 22433624
AN - SCOPUS:84858850494
VL - 5
SP - 127
EP - 137
JO - Obesity Facts
JF - Obesity Facts
SN - 1662-4025
IS - 1
ER -