Prevalence of the metabolic syndrome and its components among obese men and women in Italy

Claudio L. Lafortuna, Fiorenza Agosti, Alessandra De Col, Franca Pera, Fulvio Adorni, Alessandro Sartorio

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Objective: Assessment of the prevalence of the metabolic syndrome (MetS) and its components in Italian obese individuals. Methods: Cross-sectional estimate of MetS prevalence using the IDF definition in 635 obese (BMI ≥ 35 kg/m 2) individuals (286 men, 349 women) aged 19-78 years hospitalised for mass excess treatment. Results: MetS prevalence was significantly (p <0.001) higher in males (75.9%) than in females (61.9%), due to the increased prevalence of 4/5 involved abnormalities. A multivariate binary logistic regression analysis disclosed a contributory independent effect of ageing (p <0.01-0.001), but not of BMI, whereas large waist circumference (p <0.01) and high waist-to-hip ratio (p <0.01) contributed to MetS prevalence only in women. Affected individuals were significantly older (males p = 0.022; females p <0.001), affected men being younger than affected women (p <0.01). The prevailing clinical picture included all abnormalities (21.2% in men, 22.2% in women); in minimal trait MetS (3/5 abnormalities), the prevailing combination was, beside central obesity, hypertension-hyperglycaemia in men (12.4%), and hypertension-dyslipidemia in women (19.4%). Conclusions: MetS is a highly prevalent condition among Italian obese individuals. Prevalence and combinations of involved abnormalities differ considerably between genders and suggest a different pathophysiology of the MetS in men and women, with possible relevance for prevention and treatment of the condition.

Original languageEnglish
Pages (from-to)127-137
Number of pages11
JournalObesity Facts
Volume5
Issue number1
DOIs
Publication statusPublished - Mar 2012

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Italy
hypertension
Hypertension
Waist-Hip Ratio
Abdominal Obesity
Waist Circumference
Dyslipidemias
regression analysis
Hyperglycemia
logistics
Logistic Models
Regression Analysis
gender
Therapeutics

Keywords

  • Blood pressure
  • Fasting plasma glucose
  • HDL cholesterol
  • Obesity
  • Triglycerides

ASJC Scopus subject areas

  • Physiology (medical)
  • Health(social science)

Cite this

Prevalence of the metabolic syndrome and its components among obese men and women in Italy. / Lafortuna, Claudio L.; Agosti, Fiorenza; De Col, Alessandra; Pera, Franca; Adorni, Fulvio; Sartorio, Alessandro.

In: Obesity Facts, Vol. 5, No. 1, 03.2012, p. 127-137.

Research output: Contribution to journalArticle

Lafortuna, Claudio L. ; Agosti, Fiorenza ; De Col, Alessandra ; Pera, Franca ; Adorni, Fulvio ; Sartorio, Alessandro. / Prevalence of the metabolic syndrome and its components among obese men and women in Italy. In: Obesity Facts. 2012 ; Vol. 5, No. 1. pp. 127-137.
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